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Xray Structure of Grb2 SH2 Domain

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00017
Domain description: SH2 domain
Occurring in:
  1. Growth factor receptor-bound protein 2
The deposited structure of PDB entry 1jyu contains 1 copy of Pfam domain PF00017 (SH2 domain) in Growth factor receptor-bound protein 2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000980
Domain description: SH2 domain
Occurring in:
  1. Growth factor receptor-bound protein 2
IPR036860
Domain description: SH2 domain superfamily
Occurring in:
  1. Growth factor receptor-bound protein 2
IPR043539
Domain description: Grb2-like
Occurring in:
  1. Growth factor receptor-bound protein 2

Structure domain

CATH CATH domain
3.30.505.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: SHC Adaptor Protein
Homology: SH2 domain
Occurring in:
  1. Growth factor receptor-bound protein 2
The deposited structure of PDB entry 1jyu contains 1 copy of CATH domain 3.30.505.10 (SHC Adaptor Protein) in Growth factor receptor-bound protein 2. Showing 1 copy in chain A.
SCOP SCOP annotation
55551
Class: Alpha and beta proteins (a+b)
Fold: SH2-like
Superfamily: SH2 domain
Occurring in:
  1. Growth factor receptor-bound protein 2
The deposited structure of PDB entry 1jyu contains 1 copy of SCOP domain 55551 (SH2 domain) in Growth factor receptor-bound protein 2. Showing 1 copy in chain A.

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