Structure analysis

Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3

X-ray diffraction
2.7Å resolution
Assembly composition:
hetero tetramer (preferred)
Entry contents: 4 distinct polypeptide molecules


Assembly 1 (preferred)
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Multimeric state: hetero tetramer
Accessible surface area: 27900 Å2
Buried surface area: 8800 Å2
Dissociation area: 650 Å2
Dissociation energy (ΔGdiss): -4 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): -43 kcal/mol
Symmetry number: 1


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