› 1jqq

X-ray diffraction
2.65Å resolution

Crystal structure of Pex13p(301-386) SH3 domain

Released:
DOI: 10.2210/pdb1jqq/pdb
PDB entry 1jqq coloured by chain, front view.
PDB entry 1jqq coloured by chain, side view.
PDB entry 1jqq coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain.
Douangamath A, Filipp FV, Klein AT, Barnett P, Zou P, Voorn-Brouwer T, Vega MC, Mayans OM, Sattler M, Distel B, Wilmanns M
Mol Cell 10 1007-17 (2002)
PMID: 12453410

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160443 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisomal membrane protein PEX13 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 92 amino acids
Theoretical weight: 10.78 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P80667 (Residues: 299-386; Coverage: 23%)
Gene names: L9470.1, PAS20, PEX13, YLR191W
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2
Unit cell:
a: 104.199Å b: 50.441Å c: 74.773Å
α: 90° β: 109.04° γ: 90°
R-values:
R R work R free
0.235 0.235 0.277
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

18 review citations

Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction.
Li SS. (2005)
17 more

4 mentions without citation

Characterization of domain-peptide interaction interface: prediction of SH3 domain-mediated protein-protein interaction network in yeast by generic structure-based models.
Hou et al. (2012)
3 more