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NADH PEROXIDASE WITH CYSTEINE-SULFENIC ACID

Source organism: Enterococcus faecalis
Biochemical function: flavin adenine dinucleotide binding
Biological process: cellular oxidant detoxification
Cellular component: not assigned

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EC 1.11.1.1: NADH peroxidase

Reaction catalysed:
NADH + H(2)O(2) = NAD(+) + 2 H(2)O
Systematic name:
NADH:hydrogen-peroxide oxidoreductase
Alternative Name(s):
  • DPNH peroxidase
  • Diphosphopyridine nucleotide peroxidase
  • NAD peroxidase
  • NADH-peroxidase
  • Nicotinamide adenine dinucleotide peroxidase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF02852
Domain description: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
Occurring in:
  1. NADH peroxidase
The deposited structure of PDB entry 1joa contains 1 copy of Pfam domain PF02852 (Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain) in NADH peroxidase. Showing 1 copy in chain A.

PF00070
Domain description: Pyridine nucleotide-disulphide oxidoreductase
Occurring in:
  1. NADH peroxidase
The deposited structure of PDB entry 1joa contains 1 copy of Pfam domain PF00070 (Pyridine nucleotide-disulphide oxidoreductase) in NADH peroxidase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR036188
Domain description: FAD/NAD(P)-binding domain superfamily
Occurring in:
  1. NADH peroxidase
IPR016156
Domain description: FAD/NAD-linked reductase, dimerisation domain superfamily
Occurring in:
  1. NADH peroxidase
IPR004099
Domain description: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
Occurring in:
  1. NADH peroxidase
IPR023753
Domain description: FAD/NAD(P)-binding domain
Occurring in:
  1. NADH peroxidase

Structure domains

CATH CATH domains
3.50.50.60
Class: Alpha Beta
Architecture: 3-Layer(bba) Sandwich
Topology: FAD/NAD(P)-binding domain
Homology: FAD/NAD(P)-binding domain
Occurring in:
  1. NADH peroxidase
The deposited structure of PDB entry 1joa contains 2 copies of CATH domain 3.50.50.60 (FAD/NAD(P)-binding domain) in NADH peroxidase. Showing 2 copies in chain A.
3.30.390.30
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Enolase-like; domain 1
Homology: Enolase-like; domain 1
Occurring in:
  1. NADH peroxidase
The deposited structure of PDB entry 1joa contains 1 copy of CATH domain 3.30.390.30 (Enolase-like; domain 1) in NADH peroxidase. Showing 1 copy in chain A.
SCOP SCOP annotations
51943
Class: Alpha and beta proteins (a/b)
Fold: FAD/NAD(P)-binding domain
Superfamily: FAD/NAD(P)-binding domain
Occurring in:
  1. NADH peroxidase
The deposited structure of PDB entry 1joa contains 2 copies of SCOP domain 51943 (FAD/NAD-linked reductases, N-terminal and central domains) in NADH peroxidase. Showing 2 copies in chain A.
55425
Class: Alpha and beta proteins (a+b)
Fold: CO dehydrogenase flavoprotein C-domain-like
Superfamily: FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Occurring in:
  1. NADH peroxidase
The deposited structure of PDB entry 1joa contains 1 copy of SCOP domain 55425 (FAD/NAD-linked reductases, dimerisation (C-terminal) domain) in NADH peroxidase. Showing 1 copy in chain A.

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