Reviews - 1jm7 mentioned but not cited (13)
- RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination. Metzger MB, Pruneda JN, Klevit RE, Weissman AM. Biochim Biophys Acta 1843 47-60 (2014)
- Structural insights into the catalysis and regulation of E3 ubiquitin ligases. Buetow L, Huang DT. Nat Rev Mol Cell Biol 17 626-642 (2016)
- A guide for functional analysis of BRCA1 variants of uncertain significance. Millot GA, Carvalho MA, Caputo SM, Vreeswijk MP, Brown MA, Webb M, Rouleau E, Neuhausen SL, Hansen Tv, Galli A, Brandão RD, Blok MJ, Velkova A, Couch FJ, Monteiro AN, ENIGMA Consortium Functional Assay Working Group. Hum Mutat 33 1526-1537 (2012)
- Following Ariadne's thread: a new perspective on RBR ubiquitin ligases. Wenzel DM, Klevit RE. BMC Biol 10 24 (2012)
- The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination. Zhao W, Wiese C, Kwon Y, Hromas R, Sung P. Annu Rev Biochem 88 221-245 (2019)
- RING-Between-RING E3 Ligases: Emerging Themes amid the Variations. Dove KK, Klevit RE. J Mol Biol 429 3363-3375 (2017)
- Structural basis of homologous recombination. Sun Y, McCorvie TJ, Yates LA, Zhang X. Cell Mol Life Sci 77 3-18 (2020)
- BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies. Dever SM, White ER, Hartman MC, Valerie K. Cell Cycle 11 687-694 (2012)
- The BRCA1 Ubiquitin ligase function sets a new trend for remodelling in DNA repair. Densham RM, Morris JR. Nucleus 8 116-125 (2017)
- Fanconi anemia pathway as a prospective target for cancer intervention. Liu W, Palovcak A, Li F, Zafar A, Yuan F, Zhang Y. Cell Biosci 10 39 (2020)
- The BRCA1/BARD1 ubiquitin ligase and its substrates. Witus SR, Stewart MD, Klevit RE. Biochem J 478 3467-3483 (2021)
- BARD1 mystery: tumor suppressors are cancer susceptibility genes. Hawsawi YM, Shams A, Theyab A, Abdali WA, Hussien NA, Alatwi HE, Alzahrani OR, Oyouni AAA, Babalghith AO, Alreshidi M. BMC Cancer 22 599 (2022)
- Structural Diversity of Ubiquitin E3 Ligase. Toma-Fukai S, Shimizu T. Molecules 26 6682 (2021)
Articles - 1jm7 mentioned but not cited (54)
- Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral. Tavtigian SV, Deffenbaugh AM, Yin L, Judkins T, Scholl T, Samollow PB, de Silva D, Zharkikh A, Thomas A. J Med Genet 43 295-305 (2006)
- Accurate classification of BRCA1 variants with saturation genome editing. Findlay GM, Daza RM, Martin B, Zhang MD, Leith AP, Gasperini M, Janizek JD, Huang X, Starita LM, Shendure J. Nature 562 217-222 (2018)
- Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome. McGinty RK, Henrici RC, Tan S. Nature 514 591-596 (2014)
- Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection. Densham RM, Garvin AJ, Stone HR, Strachan J, Baldock RA, Daza-Martin M, Fletcher A, Blair-Reid S, Beesley J, Johal B, Pearl LH, Neely R, Keep NH, Watts FZ, Morris JR. Nat Struct Mol Biol 23 647-655 (2016)
- Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Markson G, Kiel C, Hyde R, Brown S, Charalabous P, Bremm A, Semple J, Woodsmith J, Duley S, Salehi-Ashtiani K, Vidal M, Komander D, Serrano L, Lehner P, Sanderson CM. Genome Res 19 1905-1911 (2009)
- Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance. Silke J, Kratina T, Chu D, Ekert PG, Day CL, Pakusch M, Huang DC, Vaux DL. Proc Natl Acad Sci U S A 102 16182-16187 (2005)
- Sequence and structural analyses of nuclear export signals in the NESdb database. Xu D, Farmer A, Collett G, Grishin NV, Chook YM. Mol Biol Cell 23 3677-3693 (2012)
- Molecular basis of Pirh2-mediated p53 ubiquitylation. Sheng Y, Laister RC, Lemak A, Wu B, Tai E, Duan S, Lukin J, Sunnerhagen M, Srisailam S, Karra M, Benchimol S, Arrowsmith CH. Nat Struct Mol Biol 15 1334-1342 (2008)
- Structure-Function Of The Tumor Suppressor BRCA1. Clark SL, Rodriguez AM, Snyder RR, Hankins GD, Boehning D. Comput Struct Biotechnol J 1 (2012)
- A Multiplex Homology-Directed DNA Repair Assay Reveals the Impact of More Than 1,000 BRCA1 Missense Substitution Variants on Protein Function. Starita LM, Islam MM, Banerjee T, Adamovich AI, Gullingsrud J, Fields S, Shendure J, Parvin JD. Am J Hum Genet 103 498-508 (2018)
- Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions. Gray VE, Hause RJ, Fowler DM. Genetics 207 53-61 (2017)
- E2 conjugating enzyme selectivity and requirements for function of the E3 ubiquitin ligase CHIP. Soss SE, Yue Y, Dhe-Paganon S, Chazin WJ. J Biol Chem 286 21277-21286 (2011)
- The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling. Zelter A, Bonomi M, Kim JO, Umbreit NT, Hoopmann MR, Johnson R, Riffle M, Jaschob D, MacCoss MJ, Moritz RL, Davis TN. Nat Commun 6 8673 (2015)
- Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1. Dove KK, Olszewski JL, Martino L, Duda DM, Wu XS, Miller DJ, Reiter KH, Rittinger K, Schulman BA, Klevit RE. Structure 25 890-900.e5 (2017)
- The Importance of Non-accessible Crosslinks and Solvent Accessible Surface Distance in Modeling Proteins with Restraints From Crosslinking Mass Spectrometry. Matthew Allen Bullock J, Schwab J, Thalassinos K, Topf M. Mol Cell Proteomics 15 2491-2500 (2016)
- Comparing interfacial dynamics in protein-protein complexes: an elastic network approach. Zen A, Micheletti C, Keskin O, Nussinov R. BMC Struct Biol 10 26 (2010)
- Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks. Lee C, Banerjee T, Gillespie J, Ceravolo A, Parvinsmith MR, Starita LM, Fields S, Toland AE, Parvin JD. Hum Mutat 36 1205-1214 (2015)
- Isotope signatures allow identification of chemically cross-linked peptides by mass spectrometry: a novel method to determine interresidue distances in protein structures through cross-linking. Zelter A, Hoopmann MR, Vernon R, Baker D, MacCoss MJ, Davis TN. J Proteome Res 9 3583-3589 (2010)
- RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. Hodge CD, Ismail IH, Edwards RA, Hura GL, Xiao AT, Tainer JA, Hendzel MJ, Glover JN. J Biol Chem 291 9396-9410 (2016)
- Crystal structure of the BARD1 ankyrin repeat domain and its functional consequences. Fox D, Le Trong I, Rajagopal P, Brzovic PS, Stenkamp RE, Klevit RE. J Biol Chem 283 21179-21186 (2008)
- Identification of functional SNPs in BARD1 gene and in silico analysis of damaging SNPs: based on data procured from dbSNP database. Alshatwi AA, Hasan TN, Syed NA, Shafi G, Grace BL. PLoS One 7 e43939 (2012)
- Evolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1 gene with missense sequence changes and in-frame deletions, but not polymorphisms. Pettigrew C, Wayte N, Lovelock PK, Tavtigian SV, Chenevix-Trench G, Spurdle AB, Brown MA. Breast Cancer Res 7 R929-39 (2005)
- Mechanism of ubiquitin transfer promoted by TRAF6. Fu TM, Shen C, Li Q, Zhang P, Wu H. Proc Natl Acad Sci U S A 115 1783-1788 (2018)
- Mutational Landscape of the BAP1 Locus Reveals an Intrinsic Control to Regulate the miRNA Network and the Binding of Protein Complexes in Uveal Melanoma. Sharma A, Biswas A, Liu H, Sen S, Paruchuri A, Katsonis P, Lichtarge O, Chand Dakal T, Maulik U, Gromiha MM, Bandyopadhyay S, Ludwig M, Holz FG, Loeffler KU, Herwig-Carl MC. Cancers (Basel) 11 (2019)
- Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms. Stewart MD, Duncan ED, Coronado E, DaRosa PA, Pruneda JN, Brzovic PS, Klevit RE. Protein Sci 26 475-483 (2017)
- A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease. Gilmore BL, Winton CE, Demmert AC, Tanner JR, Bowman S, Karageorge V, Patel K, Sheng Z, Kelly DF. Sci Rep 5 14440 (2015)
- BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1. Witus SR, Burrell AL, Farrell DP, Kang J, Wang M, Hansen JM, Pravat A, Tuttle LM, Stewart MD, Brzovic PS, Chatterjee C, Zhao W, DiMaio F, Kollman JM, Klevit RE. Nat Struct Mol Biol 28 268-277 (2021)
- A microchip platform for structural oncology applications. Winton CE, Gilmore BL, Demmert AC, Karageorge V, Sheng Z, Kelly DF. NPJ Breast Cancer 2 (2016)
- Antagonizing functions of BARD1 and its alternatively spliced variant BARD1δ in telomere stability. Pilyugin M, André PA, Ratajska M, Kuzniacka A, Limon J, Tournier BB, Colas J, Laurent G, Irminger-Finger I. Oncotarget 8 9339-9353 (2017)
- BRCA1 p.His1673del is a pathogenic mutation associated with a predominant ovarian cancer phenotype. Zuntini R, Cortesi L, Calistri D, Pippucci T, Martelli PL, Casadio R, Capizzi E, Santini D, Miccoli S, Medici V, Danesi R, Marchi I, Zampiga V, Fiorentino M, Ferrari S, Turchetti D. Oncotarget 8 22640-22648 (2017)
- Structural analysis of BRCA1 reveals modification hotspot. Liang Y, Dearnaley WJ, Varano AC, Winton CE, Gilmore BL, Alden NA, Sheng Z, Kelly DF. Sci Adv 3 e1701386 (2017)
- Targeting the lysosome by an aminomethylated Riccardin D triggers DNA damage through cathepsin B-mediated degradation of BRCA1. Wang Y, Niu H, Hu Z, Zhu M, Wang L, Han L, Qian L, Tian K, Yuan H, Lou H. J Cell Mol Med 23 1798-1812 (2019)
- Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Hu Q, Botuyan MV, Zhao D, Cui G, Mer E, Mer G. Nature 596 438-443 (2021)
- Predicting pathogenicity of missense variants with weakly supervised regression. Cao Y, Sun Y, Karimi M, Chen H, Moronfoye O, Shen Y. Hum Mutat 40 1579-1592 (2019)
- A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases. Magraner-Pardo L, Laskowski RA, Pons T, Thornton JM. Sci Rep 11 14268 (2021)
- In silico analysis for determining the deleterious nonsynonymous single nucleotide polymorphisms of BRCA genes. Yadegari F, Majidzadeh K. Mol Biol Res Commun 8 141-150 (2019)
- Correspondence between functional scores from deep mutational scans and predicted effects on protein stability. Gerasimavicius L, Livesey BJ, Marsh JA. Protein Sci 32 e4688 (2023)
- Prediction of Function Determining and Buried Residues Through Analysis of Saturation Mutagenesis Datasets. Bhasin M, Varadarajan R. Front Mol Biosci 8 635425 (2021)
- The BRCA1 variant p.Ser36Tyr abrogates BRCA1 protein function and potentially confers a moderate risk of breast cancer. Christou CM, Hadjisavvas A, Kyratzi M, Flouri C, Neophytou I, Anastasiadou V, Loizidou MA, Kyriacou K. PLoS One 9 e93400 (2014)
- The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins. Chakraborty S, Rendón-Ramírez A, Ásgeirsson B, Dutta M, Ghosh AS, Oda M, Venkatramani R, Rao BJ, Dandekar AM, Goñi FM. F1000Res 2 286 (2013)
- Zinc finger domain of the human DTX protein adopts a unique RING fold. Miyamoto K, Fujiwara Y, Saito K. Protein Sci 28 1151-1156 (2019)
- A synergetic effect of BARD1 mutations on tumorigenesis. Li W, Gu X, Liu C, Shi Y, Wang P, Zhang N, Wu R, Leng L, Xie B, Song C, Li M. Nat Commun 12 1243 (2021)
- Bayesian optimization with evolutionary and structure-based regularization for directed protein evolution. Frisby TS, Langmead CJ. Algorithms Mol Biol 16 13 (2021)
- Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans. Thapa I, Vahrenkamp R, Witus SR, Lightle C, Falkenberg O, Sellin Jeffries MK, Klevit RE, Stewart MD. Nucleic Acids Res 51 2108-2116 (2023)
- DNA repair function scores for 2172 variants in the BRCA1 amino-terminus. Diabate M, Islam MM, Nagy G, Banerjee T, Dhar S, Smith N, Adamovich AI, Starita LM, Parvin JD. PLoS Genet 19 e1010739 (2023)
- GFP-Fragment Reassembly Screens for the Functional Characterization of Variants of Uncertain Significance in Protein Interaction Domains of the BRCA1 and BRCA2 Genes. Caleca L, Colombo M, van Overeem Hansen T, Lázaro C, Manoukian S, Parsons MT, Spurdle AB, Radice P. Cancers (Basel) 11 (2019)
- Preparation of Tunable Microchips to Visualize Native Protein Complexes for Single-Particle Electron Microscopy. Gilmore BL, Varano AC, Dearnaley W, Liang Y, Marcinkowski BC, Dukes MJ, Kelly DF. Methods Mol Biol 1764 45-58 (2018)
- Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface. Thirumal Kumar D, Udhaya Kumar S, Jain N, Sowmya B, Balsekar K, Siva R, Kamaraj B, Sidenna M, George Priya Doss C, Zayed H. Adv Protein Chem Struct Biol 130 375-397 (2022)
- research-article DNA Repair Function Scores for 2172 Variants in the BRCA1 Amino-Terminus. Diabate M, Islam MM, Nagy G, Banerjee T, Dhar S, Smith N, Adamovich AI, Starita LM, Parvin JD. bioRxiv 2023.04.10.536331 (2023)
- Delineating functional mechanisms of the p53/p63/p73 family of transcription factors through identification of protein-protein interactions using interface mimicry. Guven-Maiorov E, Sakakibara N, Ponnamperuma RM, Dong K, Matar H, King KE, Weinberg WC. Mol Carcinog 61 629-642 (2022)
- Ethnic-specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population. Qin Z, Li J, Tam B, Sinha S, Zhao B, Bhaskaran SP, Huang T, Wu X, Chian JS, Guo M, Kou SH, Lei H, Zhang L, Wang X, Lagniton PNP, Xiao F, Jiang X, Wang SM. Int J Cancer 152 1159-1173 (2023)
- GC-MS profiling of Bacillus spp. metabolites with an in vitro biological activity assessment and computational analysis of their impact on epithelial glioblastoma cancer genes. Naveed M, Ishfaq H, Rehman SU, Javed A, Waseem M, Makhdoom SI, Aziz T, Alharbi M, Alshammari A, Alasmari AF. Front Chem 11 1287599 (2023)
- Novel mutations in the RING-finger domain of BRCA1 gene in clinically diagnosed breast cancer patients. Kumar PS, Srikanth L, Reddy KS, Sarma PVGK. 3 Biotech 10 47 (2020)
- Towards a New, Endophenotype-Based Strategy for Pathogenicity Prediction in BRCA1 and BRCA2: In Silico Modeling of the Outcome of HDR/SGE Assays for Missense Variants. Özkan S, Padilla N, de la Cruz X. Int J Mol Sci 22 6226 (2021)
Reviews citing this publication (72)
- Cancer susceptibility and the functions of BRCA1 and BRCA2. Venkitaraman AR. Cell 108 171-182 (2002)
- Ubiquitin: structures, functions, mechanisms. Pickart CM, Eddins MJ. Biochim Biophys Acta 1695 55-72 (2004)
- The general transcription machinery and general cofactors. Thomas MC, Chiang CM. Crit Rev Biochem Mol Biol 41 105-178 (2006)
- Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling. Uversky VN, Oldfield CJ, Dunker AK. J Mol Recognit 18 343-384 (2005)
- Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins. Prakash R, Zhang Y, Feng W, Jasin M. Cold Spring Harb Perspect Biol 7 a016600 (2015)
- BRCA1 and its toolbox for the maintenance of genome integrity. Huen MS, Sy SM, Chen J. Nat Rev Mol Cell Biol 11 138-148 (2010)
- HECT and RING finger families of E3 ubiquitin ligases at a glance. Metzger MB, Hristova VA, Weissman AM. J Cell Sci 125 531-537 (2012)
- New insights into ubiquitin E3 ligase mechanism. Berndsen CE, Wolberger C. Nat Struct Mol Biol 21 301-307 (2014)
- Zinc and human health: an update. Chasapis CT, Loutsidou AC, Spiliopoulou CA, Stefanidou ME. Arch Toxicol 86 521-534 (2012)
- Recombinational DNA repair and human disease. Thompson LH, Schild D. Mutat Res 509 49-78 (2002)
- Homologous repair of DNA damage and tumorigenesis: the BRCA connection. Jasin M. Oncogene 21 8981-8993 (2002)
- Regulation of tumor suppressors by nuclear-cytoplasmic shuttling. Fabbro M, Henderson BR. Exp Cell Res 282 59-69 (2003)
- Interactions between BRCT repeats and phosphoproteins: tangled up in two. Glover JN, Williams RS, Lee MS. Trends Biochem Sci 29 579-585 (2004)
- Linear polyubiquitination: a new regulator of NF-kappaB activation. Iwai K, Tokunaga F. EMBO Rep 10 706-713 (2009)
- BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair. O'Donovan PJ, Livingston DM. Carcinogenesis 31 961-967 (2010)
- BRCA1 gene in breast cancer. Rosen EM, Fan S, Pestell RG, Goldberg ID. J Cell Physiol 196 19-41 (2003)
- Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment. Venkitaraman AR. Annu Rev Pathol 4 461-487 (2009)
- The ubiquitin system, disease, and drug discovery. Petroski MD. BMC Biochem 9 Suppl 1 S7 (2008)
- Tracing the network connecting BRCA and Fanconi anaemia proteins. Venkitaraman AR. Nat Rev Cancer 4 266-276 (2004)
- Ubiquitin and breast cancer. Ohta T, Fukuda M. Oncogene 23 2079-2088 (2004)
- Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forks. Nagaraju G, Scully R. DNA Repair (Amst) 6 1018-1031 (2007)
- The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication. Tarsounas M, Sung P. Nat Rev Mol Cell Biol 21 284-299 (2020)
- BRCA1 regulation of transcription. Rosen EM, Fan S, Ma Y. Cancer Lett 236 175-185 (2006)
- The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy. Li M, Yu X. Oncogene 34 3349-3356 (2015)
- Genomic instability and cancer: networks involved in response to DNA damage. Eyfjord JE, Bodvarsdottir SK. Mutat Res 592 18-28 (2005)
- The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers. Paul A, Paul S. Front Biosci (Landmark Ed) 19 605-618 (2014)
- Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking. Henderson BR. Bioessays 27 884-893 (2005)
- Live and let die: insights into pseudoenzyme mechanisms from structure. Murphy JM, Mace PD, Eyers PA. Curr Opin Struct Biol 47 95-104 (2017)
- Role of BRCA Mutations in the Modulation of Response to Platinum Therapy. Mylavarapu S, Das A, Roy M. Front Oncol 8 16 (2018)
- Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network. Greenberg RA. Chromosoma 117 305-317 (2008)
- Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1. De P, Rodgers KK. Immunol Rev 200 70-82 (2004)
- BRCA1 gene: function and deficiency. Takaoka M, Miki Y. Int J Clin Oncol 23 36-44 (2018)
- Insights into the molecular basis of human hereditary breast cancer from studies of the BRCA1 BRCT domain. Glover JN. Fam Cancer 5 89-93 (2006)
- The BRCA1 ubiquitin ligase and homologous recombination repair. Ohta T, Sato K, Wu W. FEBS Lett 585 2836-2844 (2011)
- A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer. Satija YK, Bhardwaj A, Das S. Int J Cancer 133 2759-2768 (2013)
- Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination. Christensen DE, Klevit RE. FEBS J 276 5381-5389 (2009)
- Specificity and disease in the ubiquitin system. Chaugule VK, Walden H. Biochem Soc Trans 44 212-227 (2016)
- Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks. Mermershtain I, Glover JN. Mutat Res 750 15-22 (2013)
- The nucleosome: orchestrating DNA damage signaling and repair within chromatin. Agarwal P, Miller KM. Biochem Cell Biol 94 381-395 (2016)
- BRCA1 and BRCA2 in hereditary breast cancer. Scully R, Puget N. Biochimie 84 95-102 (2002)
- Molecular targeting of E3 ligases--a therapeutic approach for cancer. Lakshmanan M, Bughani U, Duraisamy S, Diwan M, Dastidar S, Ray A. Expert Opin Ther Targets 12 855-870 (2008)
- Repair of DNA Double-Strand Breaks in Heterochromatin. Watts FZ. Biomolecules 6 (2016)
- Targeting the Ubiquitin System in Glioblastoma. Scholz N, Kurian KM, Siebzehnrubl FA, Licchesi JDF. Front Oncol 10 574011 (2020)
- The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular Locations. Henderson BR. Scientifica (Cairo) 2012 796808 (2012)
- Synthetic lethality: the road to novel therapies for breast cancer. Dhillon KK, Bajrami I, Taniguchi T, Lord CJ. Endocr Relat Cancer 23 T39-55 (2016)
- BRCA1 and homologous recombination: implications from mouse embryonic development. Liu Y, Lu LY. Cell Biosci 10 49 (2020)
- Highlight: BRCA1 and BRCA2 proteins in breast cancer. Daniel DC. Microsc Res Tech 59 68-83 (2002)
- Protein ubiquitination: CHIPping away the symmetry. Schulman BA, Chen ZJ. Mol Cell 20 653-655 (2005)
- Literature Review of BARD1 as a Cancer Predisposing Gene with a Focus on Breast and Ovarian Cancers. Alenezi WM, Fierheller CT, Recio N, Tonin PN. Genes (Basel) 11 (2020)
- Concise machinery for monitoring ubiquitination activities using novel artificial RING fingers. Miyamoto K, Saito K. Protein Sci 27 1354-1363 (2018)
- How to Inactivate Human Ubiquitin E3 Ligases by Mutation. Garcia-Barcena C, Osinalde N, Ramirez J, Mayor U. Front Cell Dev Biol 8 39 (2020)
- Interplay between BRCA1 and GADD45A and Its Potential for Nucleotide Excision Repair in Breast Cancer Pathogenesis. Pietrasik S, Zajac G, Morawiec J, Soszynski M, Fila M, Blasiak J. Int J Mol Sci 21 (2020)
- Structural basis of generic versus specific E2-RING E3 interactions in protein ubiquitination. Gundogdu M, Walden H. Protein Sci 28 1758-1770 (2019)
- HRness in Breast and Ovarian Cancers. Santana Dos Santos E, Lallemand F, Petitalot A, Caputo SM, Rouleau E. Int J Mol Sci 21 (2020)
- Non-Coding Variants in BRCA1 and BRCA2 Genes: Potential Impact on Breast and Ovarian Cancer Predisposition. Santana Dos Santos E, Lallemand F, Burke L, Stoppa-Lyonnet D, Brown M, Caputo SM, Rouleau E. Cancers (Basel) 10 (2018)
- Regulation of E3 ubiquitin ligases by homotypic and heterotypic assembly. Balaji V, Hoppe T. F1000Res 9 (2020)
- Regulation of Histone Ubiquitination in Response to DNA Double Strand Breaks. Aquila L, Atanassov BS. Cells 9 (2020)
- The Effects of Genetic and Epigenetic Alterations of BARD1 on the Development of Non-Breast and Non-Gynecological Cancers. Watters AK, Seltzer ES, MacKenzie D, Young M, Muratori J, Hussein R, Sodoma AM, To J, Singh M, Zhang D. Genes (Basel) 11 (2020)
- Hereditary ovarian cancer: biology, response to chemotherapy and prognosis. Safra T. Womens Health (Lond) 5 543-553 (2009)
- BRCA1 and BRCA2 Tumor Suppressor Function in Meiosis. Li Q, Engebrecht J. Front Cell Dev Biol 9 668309 (2021)
- The Function of BARD1 in Centrosome Regulation in Cooperation with BRCA1/OLA1/RACK1. Otsuka K, Yoshino Y, Qi H, Chiba N. Genes (Basel) 11 (2020)
- BRCA1/BARD1 is a nucleosome reader and writer. Witus SR, Zhao W, Brzovic PS, Klevit RE. Trends Biochem Sci 47 582-595 (2022)
- Acetylation, Phosphorylation, Ubiquitination (Oh My!): Following Post-Translational Modifications on the Ubiquitin Road. Lacoursiere RE, Hadi D, Shaw GS. Biomolecules 12 467 (2022)
- BRCA Mutations-The Achilles Heel of Breast, Ovarian and Other Epithelial Cancers. Loboda AP, Adonin LS, Zvereva SD, Guschin DY, Korneenko TV, Telegina AV, Kondratieva OK, Frolova SE, Pestov NB, Barlev NA. Int J Mol Sci 24 4982 (2023)
- Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 as a Prime Therapeutic Target. Raimundo L, Calheiros J, Saraiva L. Cancers (Basel) 13 (2021)
- Finding significance: New perspectives in variant classification of the RAD51 regulators, BRCA2 and beyond. Rein HL, Bernstein KA. DNA Repair (Amst) 130 103563 (2023)
- How Is the Fidelity of Proteins Ensured in Terms of Both Quality and Quantity at the Endoplasmic Reticulum? Mechanistic Insights into E3 Ubiquitin Ligases. Kang JA, Jeon YJ. Int J Mol Sci 22 (2021)
- Insights in Post-Translational Modifications: Ubiquitin and SUMO. Salas-Lloret D, González-Prieto R. Int J Mol Sci 23 3281 (2022)
- New Insights into the Therapeutic Applications of CRISPR/Cas9 Genome Editing in Breast Cancer. Ahmed M, Daoud GH, Mohamed A, Harati R. Genes (Basel) 12 (2021)
- Structural and Functional Insights into GID/CTLH E3 Ligase Complexes. Maitland MER, Lajoie GA, Shaw GS, Schild-Poulter C. Int J Mol Sci 23 5863 (2022)
- The roles of E3 ubiquitin ligases in cancer progression and targeted therapy. Sampson C, Wang Q, Otkur W, Zhao H, Lu Y, Liu X, Piao HL. Clin Transl Med 13 e1204 (2023)
- Zooming into the structure-function of RING finger proteins for anti-cancer therapeutic applications. George M, Masamba P, Iwalokun BA, Kappo AP. Am J Cancer Res 13 2773-2789 (2023)
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- Analysis and prediction of leucine-rich nuclear export signals. la Cour T, Kiemer L, Mølgaard A, Gupta R, Skriver K, Brunak S. Protein Eng Des Sel 17 527-536 (2004)
- RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling. Mattiroli F, Vissers JH, van Dijk WJ, Ikpa P, Citterio E, Vermeulen W, Marteijn JA, Sixma TK. Cell 150 1182-1195 (2012)
- Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b. Buchwald G, van der Stoop P, Weichenrieder O, Perrakis A, van Lohuizen M, Sixma TK. EMBO J 25 2465-2474 (2006)
- Inherited Mutations in Women With Ovarian Carcinoma. Norquist BM, Harrell MI, Brady MF, Walsh T, Lee MK, Gulsuner S, Bernards SS, Casadei S, Yi Q, Burger RA, Chan JK, Davidson SA, Mannel RS, DiSilvestro PA, Lankes HA, Ramirez NC, King MC, Swisher EM, Birrer MJ. JAMA Oncol 2 482-490 (2016)
- E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages. Christensen DE, Brzovic PS, Klevit RE. Nat Struct Mol Biol 14 941-948 (2007)
- Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex. Brzovic PS, Keeffe JR, Nishikawa H, Miyamoto K, Fox D, Fukuda M, Ohta T, Klevit R. Proc Natl Acad Sci U S A 100 5646-5651 (2003)
- HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53. Linares LK, Hengstermann A, Ciechanover A, Müller S, Scheffner M. Proc Natl Acad Sci U S A 100 12009-12014 (2003)
- BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer. Dou H, Buetow L, Sibbet GJ, Cameron K, Huang DT. Nat Struct Mol Biol 19 876-883 (2012)
- Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins. Sun H, Leverson JD, Hunter T. EMBO J 26 4102-4112 (2007)
- Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. Rebbeck TR, Mitra N, Wan F, Sinilnikova OM, Healey S, McGuffog L, Mazoyer S, Chenevix-Trench G, Easton DF, Antoniou AC, Nathanson KL, CIMBA Consortium, Laitman Y, Kushnir A, Paluch-Shimon S, Berger R, Zidan J, Friedman E, Ehrencrona H, Stenmark-Askmalm M, Einbeigi Z, Loman N, Harbst K, Rantala J, Melin B, Huo D, Olopade OI, Seldon J, Ganz PA, Nussbaum RL, Chan SB, Odunsi K, Gayther SA, Domchek SM, Arun BK, Lu KH, Mitchell G, Karlan BY, Walsh C, Lester J, Godwin AK, Pathak H, Ross E, Daly MB, Whittemore AS, John EM, Miron A, Terry MB, Chung WK, Goldgar DE, Buys SS, Janavicius R, Tihomirova L, Tung N, Dorfling CM, van Rensburg EJ, Steele L, Neuhausen SL, Ding YC, Ejlertsen B, Gerdes AM, Hansen Tv, Ramón y Cajal T, Osorio A, Benitez J, Godino J, Tejada MI, Duran M, Weitzel JN, Bobolis KA, Sand SR, Fontaine A, Savarese A, Pasini B, Peissel B, Bonanni B, Zaffaroni D, Vignolo-Lutati F, Scuvera G, Giannini G, Bernard L, Genuardi M, Radice P, Dolcetti R, Manoukian S, Pensotti V, Gismondi V, Yannoukakos D, Fostira F, Garber J, Torres D, Rashid MU, Hamann U, Peock S, Frost D, Platte R, Evans DG, Eeles R, Davidson R, Eccles D, Cole T, Cook J, Brewer C, Hodgson S, Morrison PJ, Walker L, Porteous ME, Kennedy MJ, Izatt L, Adlard J, Donaldson A, Ellis S, Sharma P, Schmutzler RK, Wappenschmidt B, Becker A, Rhiem K, Hahnen E, Engel C, Meindl A, Engert S, Ditsch N, Arnold N, Plendl HJ, Mundhenke C, Niederacher D, Fleisch M, Sutter C, Bartram CR, Dikow N, Wang-Gohrke S, Gadzicki D, Steinemann D, Kast K, Beer M, Varon-Mateeva R, Gehrig A, Weber BH, Stoppa-Lyonnet D, Sinilnikova OM, Mazoyer S, Houdayer C, Belotti M, Gauthier-Villars M, Damiola F, Boutry-Kryza N, Lasset C, Sobol H, Peyrat JP, Muller D, Fricker JP, Collonge-Rame MA, Mortemousque I, Nogues C, Rouleau E, Isaacs C, De Paepe A, Poppe B, Claes K, De Leeneer K, Piedmonte M, Rodriguez G, Wakely K, Boggess J, Blank SV, Basil J, Azodi M, Phillips KA, Caldes T, de la Hoya M, Romero A, Nevanlinna H, Aittomäki K, van der Hout AH, Hogervorst FB, Verhoef S, Collée JM, Seynaeve C, Oosterwijk JC, Gille JJ, Wijnen JT, Gómez Garcia EB, Kets CM, Ausems MG, Aalfs CM, Devilee P, Mensenkamp AR, Kwong A, Olah E, Papp J, Diez O, Lazaro C, Darder E, Blanco I, Salinas M, Jakubowska A, Lubinski J, Gronwald J, Jaworska-Bieniek K, Durda K, Sukiennicki G, Huzarski T, Byrski T, Cybulski C, Toloczko-Grabarek A, Złowocka-Perłowska E, Menkiszak J, Arason A, Barkardottir RB, Simard J, Laframboise R, Montagna M, Agata S, Alducci E, Peixoto A, Teixeira MR, Spurdle AB, Lee MH, Park SK, Kim SW, Friebel TM, Couch FJ, Lindor NM, Pankratz VS, Guidugli L, Wang X, Tischkowitz M, Foretova L, Vijai J, Offit K, Robson M, Rau-Murthy R, Kauff N, Fink-Retter A, Singer CF, Rappaport C, Gschwantler-Kaulich D, Pfeiler G, Tea MK, Berger A, Greene MH, Mai PL, Imyanitov EN, Toland AE, Senter L, Bojesen A, Pedersen IS, Skytte AB, Sunde L, Thomassen M, Moeller ST, Kruse TA, Jensen UB, Caligo MA, Aretini P, Teo SH, Selkirk CG, Hulick PJ, Andrulis I. JAMA 313 1347-1361 (2015)
- Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans. Linke K, Mace PD, Smith CA, Vaux DL, Silke J, Day CL. Cell Death Differ 15 841-848 (2008)
- BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number. Starita LM, Machida Y, Sankaran S, Elias JE, Griffin K, Schlegel BP, Gygi SP, Parvin JD. Mol Cell Biol 24 8457-8466 (2004)
- Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains. Mallery DL, Vandenberg CJ, Hiom K. EMBO J 21 6755-6762 (2002)
- BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP. Yu X, Fu S, Lai M, Baer R, Chen J. Genes Dev 20 1721-1726 (2006)
- Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R. Mol Cell 12 1087-1099 (2003)
- Structural mechanisms underlying posttranslational modification by ubiquitin-like proteins. Dye BT, Schulman BA. Annu Rev Biophys Biomol Struct 36 131-150 (2007)
- Structural insights into the U-box, a domain associated with multi-ubiquitination. Ohi MD, Vander Kooi CW, Rosenberg JA, Chazin WJ, Gould KL. Nat Struct Biol 10 250-255 (2003)
- The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity. Poyurovsky MV, Priest C, Kentsis A, Borden KL, Pan ZQ, Pavletich N, Prives C. EMBO J 26 90-101 (2007)
- A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein. Foray N, Marot D, Gabriel A, Randrianarison V, Carr AM, Perricaudet M, Ashworth A, Jeggo P. EMBO J 22 2860-2871 (2003)
- Massively Parallel Functional Analysis of BRCA1 RING Domain Variants. Starita LM, Young DL, Islam M, Kitzman JO, Gullingsrud J, Hause RJ, Fowler DM, Parvin JD, Shendure J, Fields S. Genetics 200 413-422 (2015)
- Cancer suppression by the chromosome custodians, BRCA1 and BRCA2. Venkitaraman AR. Science 343 1470-1475 (2014)
- Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein. Xia Y, Pao GM, Chen HW, Verma IM, Hunter T. J Biol Chem 278 5255-5263 (2003)
- A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction. Diaz-Griffero F, Qin XR, Hayashi F, Kigawa T, Finzi A, Sarnak Z, Lienlaf M, Yokoyama S, Sodroski J. J Virol 83 10737-10751 (2009)
- GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability. Hu WL, Jin L, Xu A, Wang YF, Thorne RF, Zhang XD, Wu M. Nat Cell Biol 20 492-502 (2018)
- A conserved catalytic residue in the ubiquitin-conjugating enzyme family. Wu PY, Hanlon M, Eddins M, Tsui C, Rogers RS, Jensen JP, Matunis MJ, Weissman AM, Wolberger C, Pickart CM. EMBO J 22 5241-5250 (2003)
- Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions? Mark WY, Liao JC, Lu Y, Ayed A, Laister R, Szymczyna B, Chakrabartty A, Arrowsmith CH. J Mol Biol 345 275-287 (2005)
- A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites. Polanowska J, Martin JS, Garcia-Muse T, Petalcorin MI, Boulton SJ. EMBO J 25 2178-2188 (2006)
- CCDC98 targets BRCA1 to DNA damage sites. Liu Z, Wu J, Yu X. Nat Struct Mol Biol 14 716-720 (2007)
- Mechanism of ubiquitylation by dimeric RING ligase RNF4. Plechanovová A, Jaffray EG, McMahon SA, Johnson KA, Navrátilová I, Naismith JH, Hay RT. Nat Struct Mol Biol 18 1052-1059 (2011)
- BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans. Boulton SJ, Martin JS, Polanowska J, Hill DE, Gartner A, Vidal M. Curr Biol 14 33-39 (2004)
- Mechanism of p53 stabilization by ATM after DNA damage. Cheng Q, Chen J. Cell Cycle 9 472-478 (2010)
- Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation. Tanny JC, Erdjument-Bromage H, Tempst P, Allis CD. Genes Dev 21 835-847 (2007)
- A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8. Huang DT, Miller DW, Mathew R, Cassell R, Holton JM, Roussel MF, Schulman BA. Nat Struct Mol Biol 11 927-935 (2004)
- Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays. Lee MS, Green R, Marsillac SM, Coquelle N, Williams RS, Yeung T, Foo D, Hau DD, Hui B, Monteiro AN, Glover JN. Cancer Res 70 4880-4890 (2010)
- Inactivation of effector caspases through nondegradative polyubiquitylation. Ditzel M, Broemer M, Tenev T, Bolduc C, Lee TV, Rigbolt KT, Elliott R, Zvelebil M, Blagoev B, Bergmann A, Meier P. Mol Cell 32 540-553 (2008)
- Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. Bentley ML, Corn JE, Dong KC, Phung Q, Cheung TK, Cochran AG. EMBO J 30 3285-3297 (2011)
- Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53. Kostic M, Matt T, Martinez-Yamout MA, Dyson HJ, Wright PE. J Mol Biol 363 433-450 (2006)
- Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression. Choudhury AD, Xu H, Baer R. J Biol Chem 279 33909-33918 (2004)
- Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination. Ransburgh DJ, Chiba N, Ishioka C, Toland AE, Parvin JD. Cancer Res 70 988-995 (2010)
- Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability. McCarthy EE, Celebi JT, Baer R, Ludwig T. Mol Cell Biol 23 5056-5063 (2003)
- A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. Luijsterburg MS, Acs K, Ackermann L, Wiegant WW, Bekker-Jensen S, Larsen DH, Khanna KK, van Attikum H, Mailand N, Dantuma NP. EMBO J 31 2511-2527 (2012)
- Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility. Morris JR, Pangon L, Boutell C, Katagiri T, Keep NH, Solomon E. Hum Mol Genet 15 599-606 (2006)
- BRCA1 is a histone-H2A-specific ubiquitin ligase. Kalb R, Mallery DL, Larkin C, Huang JT, Hiom K. Cell Rep 8 999-1005 (2014)
- BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks. Westermark UK, Reyngold M, Olshen AB, Baer R, Jasin M, Moynahan ME. Mol Cell Biol 23 7926-7936 (2003)
- Control of biochemical reactions through supramolecular RING domain self-assembly. Kentsis A, Gordon RE, Borden KL. Proc Natl Acad Sci U S A 99 15404-15409 (2002)
- MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination. Badciong JC, Haas AL. J Biol Chem 277 49668-49675 (2002)
- BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork. Long DT, Joukov V, Budzowska M, Walter JC. Mol Cell 56 174-185 (2014)
- Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity. Koliopoulos MG, Esposito D, Christodoulou E, Taylor IA, Rittinger K. EMBO J 35 1204-1218 (2016)
- Self-assembly properties of a model RING domain. Kentsis A, Gordon RE, Borden KL. Proc Natl Acad Sci U S A 99 667-672 (2002)
- Evolution of the tumor suppressor BRCA1 locus in primates: implications for cancer predisposition. Pavlicek A, Noskov VN, Kouprina N, Barrett JC, Jurka J, Larionov V. Hum Mol Genet 13 2737-2751 (2004)
- Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway. Sanchez JG, Chiang JJ, Sparrer KMJ, Alam SL, Chi M, Roganowicz MD, Sankaran B, Gack MU, Pornillos O. Cell Rep 16 1315-1325 (2016)
- The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases. Vander Kooi CW, Ohi MD, Rosenberg JA, Oldham ML, Newcomer ME, Gould KL, Chazin WJ. Biochemistry 45 121-130 (2006)
- Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease. Beasley SA, Hristova VA, Shaw GS. Proc Natl Acad Sci U S A 104 3095-3100 (2007)
- Solution structure of the partially folded high-risk human papilloma virus 45 oncoprotein E7. Ohlenschläger O, Seiboth T, Zengerling H, Briese L, Marchanka A, Ramachandran R, Baum M, Korbas M, Meyer-Klaucke W, Dürst M, Görlach M. Oncogene 25 5953-5959 (2006)
- Structural consequences of a cancer-causing BRCA1-BRCT missense mutation. Williams RS, Glover JN. J Biol Chem 278 2630-2635 (2003)
- Characterization of Arabidopsis thaliana ortholog of the human breast cancer susceptibility gene 1: AtBRCA1, strongly induced by gamma rays. Lafarge S, Montané MH. Nucleic Acids Res 31 1148-1155 (2003)
- Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha. Lienlaf M, Hayashi F, Di Nunzio F, Tochio N, Kigawa T, Yokoyama S, Diaz-Griffero F. J Virol 85 8725-8737 (2011)
- Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification. Notenboom V, Hibbert RG, van Rossum-Fikkert SE, Olsen JV, Mann M, Sixma TK. Nucleic Acids Res 35 5819-5830 (2007)
- Solution structure of the RBCC/TRIM B-box1 domain of human MID1: B-box with a RING. Massiah MA, Simmons BN, Short KM, Cox TC. J Mol Biol 358 532-545 (2006)
- Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage. Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T. Cancer Res 75 1311-1321 (2015)
- Nuclear-cytoplasmic shuttling of BARD1 contributes to its proapoptotic activity and is regulated by dimerization with BRCA1. Rodriguez JA, Schüchner S, Au WW, Fabbro M, Henderson BR. Oncogene 23 1809-1820 (2004)
- Autoubiquitylation of the V(D)J recombinase protein RAG1. Jones JM, Gellert M. Proc Natl Acad Sci U S A 100 15446-15451 (2003)
- BARD1 regulates BRCA1 apoptotic function by a mechanism involving nuclear retention. Fabbro M, Schuechner S, Au WW, Henderson BR. Exp Cell Res 298 661-673 (2004)
- Hetero-oligomerization with MdmX rescues the ubiquitin/Nedd8 ligase activity of RING finger mutants of Mdm2. Singh RK, Iyappan S, Scheffner M. J Biol Chem 282 10901-10907 (2007)
- Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage. Cheng Q, Cross B, Li B, Chen L, Li Z, Chen J. Mol Cell Biol 31 4951-4963 (2011)
- SUMO chain-induced dimerization activates RNF4. Rojas-Fernandez A, Plechanovová A, Hattersley N, Jaffray E, Tatham MH, Hay RT. Mol Cell 53 880-892 (2014)
- The BRCA1 RING and BRCT domains cooperate in targeting BRCA1 to ionizing radiation-induced nuclear foci. Au WW, Henderson BR. J Biol Chem 280 6993-7001 (2005)
- Packing, specificity, and mutability at the binding interface between the p160 coactivator and CREB-binding protein. Demarest SJ, Deechongkit S, Dyson HJ, Evans RM, Wright PE. Protein Sci 13 203-210 (2004)
- BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit. Benezra M, Chevallier N, Morrison DJ, MacLachlan TK, El-Deiry WS, Licht JD. J Biol Chem 278 26333-26341 (2003)
- Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation. Foray N, Marot D, Randrianarison V, Venezia ND, Picard D, Perricaudet M, Favaudon V, Jeggo P. Mol Cell Biol 22 4020-4032 (2002)
- RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin. Yudina Z, Roa A, Johnson R, Biris N, de Souza Aranha Vieira DA, Tsiperson V, Reszka N, Taylor AB, Hart PJ, Demeler B, Diaz-Griffero F, Ivanov DN. Cell Rep 12 788-797 (2015)
- Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation. Campbell SJ, Edwards RA, Leung CC, Neculai D, Hodge CD, Dhe-Paganon S, Glover JN. J Biol Chem 287 23900-23910 (2012)
- A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time. Li YC, Rodewald LW, Hoppmann C, Wong ET, Lebreton S, Safar P, Patek M, Wang L, Wertman KF, Wahl GM. Cell Rep 9 1946-1958 (2014)
- Nuclear-cytoplasmic translocation of BARD1 is linked to its apoptotic activity. Jefford CE, Feki A, Harb J, Krause KH, Irminger-Finger I. Oncogene 23 3509-3520 (2004)
- DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer. Woditschka S, Evans L, Duchnowska R, Reed LT, Palmieri D, Qian Y, Badve S, Sledge G, Gril B, Aladjem MI, Fu H, Flores NM, Gökmen-Polar Y, Biernat W, Szutowicz-Zielińska E, Mandat T, Trojanowski T, Och W, Czartoryska-Arlukowicz B, Jassem J, Mitchell JB, Steeg PS. J Natl Cancer Inst 106 (2014)
- Structural determinants of the BRCA1 : estrogen receptor interaction. Ma YX, Tomita Y, Fan S, Wu K, Tong Y, Zhao Z, Song LN, Goldberg ID, Rosen EM. Oncogene 24 1831-1846 (2005)
- BRCA1 in the DNA damage response and at telomeres. Rosen EM. Front Genet 4 85 (2013)
- The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination. Lu CS, Truong LN, Aslanian A, Shi LZ, Li Y, Hwang PY, Koh KH, Hunter T, Yates JR, Berns MW, Wu X. J Biol Chem 287 43984-43994 (2012)
- Tripartite motif ligases catalyze polyubiquitin chain formation through a cooperative allosteric mechanism. Streich FC, Ronchi VP, Connick JP, Haas AL. J Biol Chem 288 8209-8221 (2013)
- A compartmentalized signaling network mediates crossover control in meiosis. Zhang L, Köhler S, Rillo-Bohn R, Dernburg AF. Elife 7 (2018)
- Identification and characterization of missense alterations in the BRCA1 associated RING domain (BARD1) gene in breast and ovarian cancer. Sauer MK, Andrulis IL. J Med Genet 42 633-638 (2005)
- Proximity-induced activation of human Cdc34 through heterologous dimerization. Gazdoiu S, Yamoah K, Wu K, Escalante CR, Tappin I, Bermudez V, Aggarwal AK, Hurwitz J, Pan ZQ. Proc Natl Acad Sci U S A 102 15053-15058 (2005)
- Zebrafish Mib and Mib2 are mutual E3 ubiquitin ligases with common and specific delta substrates. Zhang C, Li Q, Jiang YJ. J Mol Biol 366 1115-1128 (2007)
- Active site residues and amino acid specificity of the ubiquitin carrier protein-binding RING-H2 finger domain. Katoh S, Tsunoda Y, Murata K, Minami E, Katoh E. J Biol Chem 280 41015-41024 (2005)
- Mutations in the BRCT binding site of BRCA1 result in hyper-recombination. Dever SM, Golding SE, Rosenberg E, Adams BR, Idowu MO, Quillin JM, Valerie N, Xu B, Povirk LF, Valerie K. Aging (Albany NY) 3 515-532 (2011)
- The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2. Swuec P, Renault L, Borg A, Shah F, Murphy VJ, van Twest S, Snijders AP, Deans AJ, Costa A. Cell Rep 18 611-623 (2017)
- The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity. Ii T, Fung J, Mullen JR, Brill SJ. Cell Cycle 6 2800-2809 (2007)
- bloodthirsty, an RBCC/TRIM gene required for erythropoiesis in zebrafish. Yergeau DA, Cornell CN, Parker SK, Zhou Y, Detrich HW. Dev Biol 283 97-112 (2005)
- Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2. Shloush J, Vlassov JE, Engson I, Duan S, Saridakis V, Dhe-Paganon S, Raught B, Sheng Y, Arrowsmith CH. J Biol Chem 286 4796-4808 (2011)
- Structure of the Fanconi anaemia monoubiquitin ligase complex. Shakeel S, Rajendra E, Alcón P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA. Nature 575 234-237 (2019)
- Synthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5. Carlile CM, Pickart CM, Matunis MJ, Cohen RE. J Biol Chem 284 29326-29334 (2009)
- Autoregulation of MARCH1 expression by dimerization and autoubiquitination. Bourgeois-Daigneault MC, Thibodeau J. J Immunol 188 4959-4970 (2012)
- BARD1 translocation to mitochondria correlates with Bax oligomerization, loss of mitochondrial membrane potential, and apoptosis. Tembe V, Henderson BR. J Biol Chem 282 20513-20522 (2007)
- An analysis of unclassified missense substitutions in human BRCA1. Tavtigian SV, Samollow PB, de Silva D, Thomas A. Fam Cancer 5 77-88 (2006)
- Msl1-mediated dimerization of the dosage compensation complex is essential for male X-chromosome regulation in Drosophila. Hallacli E, Lipp M, Georgiev P, Spielman C, Cusack S, Akhtar A, Kadlec J. Mol Cell 48 587-600 (2012)
- Structural and functional characterization of the monomeric U-box domain from E4B. Nordquist KA, Dimitrova YN, Brzovic PS, Ridenour WB, Munro KA, Soss SE, Caprioli RM, Klevit RE, Chazin WJ. Biochemistry 49 347-355 (2010)
- Identification of BARD1 splice-isoforms involved in human trophoblast invasion. Li L, Cohen M, Wu J, Sow MH, Nikolic B, Bischof P, Irminger-Finger I. Int J Biochem Cell Biol 39 1659-1672 (2007)
- Impact of BRCA1 BRCT domain missense substitutions on phosphopeptide recognition. Coquelle N, Green R, Glover JN. Biochemistry 50 4579-4589 (2011)
- The MID1 E3 ligase catalyzes the polyubiquitination of Alpha4 (α4), a regulatory subunit of protein phosphatase 2A (PP2A): novel insights into MID1-mediated regulation of PP2A. Du H, Huang Y, Zaghlula M, Walters E, Cox TC, Massiah MA. J Biol Chem 288 21341-21350 (2013)
- The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors. Peng Y, Liao Q, Tan W, Peng C, Hu Z, Chen Y, Li Z, Li J, Zhen B, Zhu W, Li X, Yao Y, Song Q, Liu C, Qi X, He F, Pei H. Nat Commun 10 1224 (2019)
- AKT regulates BRCA1 stability in response to hormone signaling. Nelson AC, Lyons TR, Young CD, Hansen KC, Anderson SM, Holt JT. Mol Cell Endocrinol 319 129-142 (2010)
- An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1. Yi C, Wang H, Wei N, Deng XW. BMC Cell Biol 3 30 (2002)
- BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes. Stewart MD, Zelin E, Dhall A, Walsh T, Upadhyay E, Corn JE, Chatterjee C, King MC, Klevit RE. Proc Natl Acad Sci U S A 115 1316-1321 (2018)
- Cooperative metal binding and helical folding in model peptides of treble-clef zinc fingers. Sénèque O, Bonnet E, Joumas FL, Latour JM. Chemistry 15 4798-4810 (2009)
- Re-engineering a split-GFP reassembly screen to examine RING-domain interactions between BARD1 and BRCA1 mutants observed in cancer patients. Sarkar M, Magliery TJ. Mol Biosyst 4 599-605 (2008)
- The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50. Edwards RA, Lee MS, Tsutakawa SE, Williams RS, Nazeer I, Kleiman FE, Tainer JA, Glover JN. Biochemistry 47 11446-11456 (2008)
- The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by the platinum-based anticancer drugs. Atipairin A, Canyuk B, Ratanaphan A. Breast Cancer Res Treat 126 203-209 (2011)
- Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A-RAD18 ternary complex. Masuda Y, Suzuki M, Kawai H, Suzuki F, Kamiya K. Nucleic Acids Res 40 1065-1076 (2012)
- Protein-protein interactions regulate Ubl conjugation. Knipscheer P, Sixma TK. Curr Opin Struct Biol 17 665-673 (2007)
- RNF168 forms a functional complex with RAD6 during the DNA damage response. Liu C, Wang D, Wu J, Keller J, Ma T, Yu X. J Cell Sci 126 2042-2051 (2013)
- Schizosaccharomyces pombe Rtf2 mediates site-specific replication termination by inhibiting replication restart. Inagawa T, Yamada-Inagawa T, Eydmann T, Mian IS, Wang TS, Dalgaard JZ. Proc Natl Acad Sci U S A 106 7927-7932 (2009)
- Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52. Hennig J, Ottosson L, Andrésen C, Horvath L, Kuchroo VK, Broo K, Wahren-Herlenius M, Sunnerhagen M. J Biol Chem 280 33250-33261 (2005)
- The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans. Li Q, Saito TT, Martinez-Garcia M, Deshong AJ, Nadarajan S, Lawrence KS, Checchi PM, Colaiacovo MP, Engebrecht J. PLoS Genet 14 e1007701 (2018)
- BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2. Hill DA, de la Serna IL, Veal TM, Imbalzano AN. J Cell Biochem 91 987-998 (2004)
- Impact of RING and BRCT domain mutations on BRCA1 protein stability, localization and recruitment to DNA damage. Nelson AC, Holt JT. Radiat Res 174 1-13 (2010)
- Structure, interactions, and dynamics of the RING domain from human TRAF6. Mercier P, Lewis MJ, Hau DD, Saltibus LF, Xiao W, Spyracopoulos L. Protein Sci 16 602-614 (2007)
- BRIZ1 and BRIZ2 proteins form a heteromeric E3 ligase complex required for seed germination and post-germination growth in Arabidopsis thaliana. Hsia MM, Callis J. J Biol Chem 285 37070-37081 (2010)
- Genomic analysis of inherited breast cancer among Palestinian women: Genetic heterogeneity and a founder mutation in TP53. Lolas Hamameh S, Renbaum P, Kamal L, Dweik D, Salahat M, Jaraysa T, Abu Rayyan A, Casadei S, Mandell JB, Gulsuner S, Lee MK, Walsh T, King MC, Levy-Lahad E, Kanaan M. Int J Cancer 141 750-756 (2017)
- Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. Patel VL, Busch EL, Friebel TM, Cronin A, Leslie G, McGuffog L, Adlard J, Agata S, Agnarsson BA, Ahmed M, Aittomäki K, Alducci E, Andrulis IL, Arason A, Arnold N, Artioli G, Arver B, Auber B, Azzollini J, Balmaña J, Barkardottir RB, Barnes DR, Barroso A, Barrowdale D, Belotti M, Benitez J, Bertelsen B, Blok MJ, Bodrogi I, Bonadona V, Bonanni B, Bondavalli D, Boonen SE, Borde J, Borg A, Bradbury AR, Brady A, Brewer C, Brunet J, Buecher B, Buys SS, Cabezas-Camarero S, Caldés T, Caliebe A, Caligo MA, Calvello M, Campbell IG, Carnevali I, Carrasco E, Chan TL, Chu ATW, Chung WK, Claes KBM, Collaborators GS, Collaborators E, Cook J, Cortesi L, Couch FJ, Daly MB, Damante G, Darder E, Davidson R, de la Hoya M, Puppa LD, Dennis J, Díez O, Ding YC, Ditsch N, Domchek SM, Donaldson A, Dworniczak B, Easton DF, Eccles DM, Eeles RA, Ehrencrona H, Ejlertsen B, Engel C, Evans DG, Faivre L, Faust U, Feliubadaló L, Foretova L, Fostira F, Fountzilas G, Frost D, García-Barberán V, Garre P, Gauthier-Villars M, Géczi L, Gehrig A, Gerdes AM, Gesta P, Giannini G, Glendon G, Godwin AK, Goldgar DE, Greene MH, Gutierrez-Barrera AM, Hahnen E, Hamann U, Hauke J, Herold N, Hogervorst FBL, Honisch E, Hopper JL, Hulick PJ, Investigators K, Investigators H, Izatt L, Jager A, James P, Janavicius R, Jensen UB, Jensen TD, Johannsson OT, John EM, Joseph V, Kang E, Kast K, Kiiski JI, Kim SW, Kim Z, Ko KP, Konstantopoulou I, Kramer G, Krogh L, Kruse TA, Kwong A, Larsen M, Lasset C, Lautrup C, Lazaro C, Lee J, Lee JW, Lee MH, Lemke J, Lesueur F, Liljegren A, Lindblom A, Llovet P, Lopez-Fernández A, Lopez-Perolio I, Lorca V, Loud JT, Ma ESK, Mai PL, Manoukian S, Mari V, Martin L, Matricardi L, Mebirouk N, Medici V, Meijers-Heijboer HEJ, Meindl A, Mensenkamp AR, Miller C, Gomes DM, Montagna M, Mooij TM, Moserle L, Mouret-Fourme E, Mulligan AM, Nathanson KL, Navratilova M, Nevanlinna H, Niederacher D, Nielsen FCC, Nikitina-Zake L, Offit K, Olah E, Olopade OI, Ong KR, Osorio A, Ott CE, Palli D, Park SK, Parsons MT, Pedersen IS, Peissel B, Peixoto A, Pérez-Segura P, Peterlongo P, Petersen AH, Porteous ME, Pujana MA, Radice P, Ramser J, Rantala J, Rashid MU, Rhiem K, Rizzolo P, Robson ME, Rookus MA, Rossing CM, Ruddy KJ, Santos C, Saule C, Scarpitta R, Schmutzler RK, Schuster H, Senter L, Seynaeve CM, Shah PD, Sharma P, Shin VY, Silvestri V, Simard J, Singer CF, Skytte AB, Snape K, Solano AR, Soucy P, Southey MC, Spurdle AB, Steele L, Steinemann D, Stoppa-Lyonnet D, Stradella A, Sunde L, Sutter C, Tan YY, Teixeira MR, Teo SH, Thomassen M, Tibiletti MG, Tischkowitz M, Tognazzo S, Toland AE, Tommasi S, Torres D, Toss A, Trainer AH, Tung N, van Asperen CJ, van der Baan FH, van der Kolk LE, van der Luijt RB, van Hest LP, Varesco L, Varon-Mateeva R, Viel A, Vierstraete J, Villa R, von Wachenfeldt A, Wagner P, Wang-Gohrke S, Wappenschmidt B, Weitzel JN, Wieme G, Yadav S, Yannoukakos D, Yoon SY, Zanzottera C, Zorn KK, D'Amico AV, Freedman ML, Pomerantz MM, Chenevix-Trench G, Antoniou AC, Neuhausen SL, Ottini L, Nielsen HR, Rebbeck TR. Cancer Res 80 624-638 (2020)
- The tripartite motif of nuclear factor 7 is required for its association with transcriptional units. Beenders B, Jones PL, Bellini M. Mol Cell Biol 27 2615-2624 (2007)
- A common Greenlandic Inuit BRCA1 RING domain founder mutation. Hansen TV, Ejlertsen B, Albrechtsen A, Bergsten E, Bjerregaard P, Hansen T, Myrhøj T, Nielsen PB, Timmermans-Wielenga V, Andersen MK, Jønson L, Nielsen FC. Breast Cancer Res Treat 115 69-76 (2009)
- Cancer risks in first degree relatives of BRCA1 mutation carriers: effects of mutation and proband disease status. Gronwald J, Huzarski T, Byrski B, Medrek K, Menkiszak J, Monteiro AN, Sun P, Lubinski J, Narod SA. J Med Genet 43 424-428 (2006)
- Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer. Weber-Lassalle N, Borde J, Weber-Lassalle K, Horváth J, Niederacher D, Arnold N, Kaulfuß S, Ernst C, Paul VG, Honisch E, Klaschik K, Volk AE, Kubisch C, Rapp S, Lichey N, Altmüller J, Lepkes L, Pohl-Rescigno E, Thiele H, Nürnberg P, Larsen M, Richters L, Rhiem K, Wappenschmidt B, Engel C, Meindl A, Schmutzler RK, Hahnen E, Hauke J. Breast Cancer Res 21 55 (2019)
- Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation. Kim S, Jin H, Seo HR, Lee HJ, Lee YS. Cell Death Differ 26 812-825 (2019)
- The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1. Middleton AJ, Budhidarmo R, Das A, Zhu J, Foglizzo M, Mace PD, Day CL. Nat Commun 8 1788 (2017)
- The fellowship of the RING: the RING-B-box linker region interacts with the RING in TRIM21/Ro52, contains a native autoantigenic epitope in Sjögren syndrome, and is an integral and conserved region in TRIM proteins. Hennig J, Bresell A, Sandberg M, Hennig KD, Wahren-Herlenius M, Persson B, Sunnerhagen M. J Mol Biol 377 431-449 (2008)
- Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains. Corcoran CA, Montalbano J, Sun H, He Q, Huang Y, Sheikh MS. J Biol Chem 284 21955-21970 (2009)
- NMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligase. Chasapis CT, Kandias NG, Episkopou V, Bentrop D, Spyroulias GA. Proteins 80 1484-1489 (2012)
- "DNA Binding Region" of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase Checkpoint. Masuda T, Xu X, Dimitriadis EK, Lahusen T, Deng CX. Int J Biol Sci 12 133-143 (2016)
- Caveolin-1 controls BRCA1 gene expression and cellular localization in human breast cancer cells. Glait C, Ravid D, Lee SW, Liscovitch M, Werner H. FEBS Lett 580 5268-5274 (2006)
- High yield expression and NMR characterization of Arkadia E3 ubiquitin ligase RING-H2 finger domain. Kandias NG, Chasapis CT, Bentrop D, Episkopou V, Spyroulias GA. Biochem Biophys Res Commun 378 498-502 (2009)
- Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations. Nominé Y, Botuyan MV, Bajzer Z, Owen WG, Caride AJ, Wasielewski E, Mer G. Biochemistry 47 9866-9879 (2008)
- Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutation. Whiley PJ, Parsons MT, Leary J, Tucker K, Warwick L, Dopita B, Thorne H, Lakhani SR, Goldgar DE, Brown MA, Spurdle AB. PLoS One 9 e86836 (2014)
- BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites. Hu Z, Mi S, Zhao T, Peng C, Peng Y, Chen L, Zhu W, Yao Y, Song Q, Li X, Li X, Jia C, Pei H. EMBO J 39 e104133 (2020)
- C. elegans ZHP-4 is required at multiple distinct steps in the formation of crossovers and their transition to segregation competent chiasmata. Nguyen H, Labella S, Silva N, Jantsch V, Zetka M. PLoS Genet 14 e1007776 (2018)
- NMR assignment of the arenaviral protein Z from Lassa fever virus. Volpon L, Osborne MJ, Borden KL. Biomol NMR Assign 2 81-84 (2008)
- Purification and characterisation of a soluble N-terminal fragment of the breast cancer susceptibility protein BRCA1. Sturdy A, Naseem R, Webb M. J Mol Biol 340 469-475 (2004)
- A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity. Birkou M, Chasapis CT, Marousis KD, Loutsidou AK, Bentrop D, Lelli M, Herrmann T, Carthy JM, Episkopou V, Spyroulias GA. J Mol Biol 429 2373-2386 (2017)
- Analysis of the DNA binding activity of BRCA1 and its modulation by the tumour suppressor p53. Naseem R, Webb M. PLoS One 3 e2336 (2008)
- Structural model of ubiquitin transfer onto an artificial RING finger as an E3 ligase. Miyamoto K. Sci Rep 4 6574 (2014)
- A RING domain gene is expressed in different cell types of leaf trace, stem, and juvenile bundles in the stem vascular system of zinnia. Dahiya P, Milioni D, Wells B, Stacey N, Roberts K, McCann MC. Plant Physiol 138 1383-1395 (2005)
- An adenoviral vector containing an arg-gly-asp (RGD) motif in the fiber knob enhances protein product levels from transgenes refractory to expression. Campbell M, Qu S, Wells S, Sugandha H, Jensen RA. Cancer Gene Ther 10 559-570 (2003)
- BARD1 regulates BRCA1-mediated transactivation of the p21WAF1/CIP1 and Gadd45 promoters. Fabbro M, Henderson BR. Cancer Lett 263 189-196 (2008)
- BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1. Zou J, Zhang D, Qin G, Chen X, Wang H, Zhang D. Cell Cycle 13 3685-3697 (2014)
- Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B. Foglizzo M, Middleton AJ, Day CL. J Mol Biol 428 4073-4086 (2016)
- The in vivo dynamic organization of BRCA1-A complex proteins at DNA damage-induced nuclear foci. Mok MT, Henderson BR. Traffic 13 800-814 (2012)
- Cisplatin affects the conformation of apo form, not holo form, of BRCA1 RING finger domain and confers thermal stability. Atipairin A, Canyuk B, Ratanaphan A. Chem Biodivers 7 1949-1967 (2010)
- Highly sensitive detection of E2 activity in ubiquitination using an artificial RING finger. Miyamoto K, Sumida M, Yuasa-Sunagawa M, Saito K. J Pept Sci 23 222-227 (2017)
- Interferon-γ signaling is associated with BRCA1 loss-of-function mutations in high grade serous ovarian cancer. Cardenas H, Jiang G, Thomes Pepin J, Parker JB, Condello S, Nephew KP, Nakshatri H, Chakravarti D, Liu Y, Matei D. NPJ Precis Oncol 3 32 (2019)
- Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: implications for genetic screening of Greenlandic Inuit families with high risk for breast and/or ovarian cancer. Hansen TV, Jønson L, Albrechtsen A, Steffensen AY, Bergsten E, Myrhøj T, Ejlertsen B, Nielsen FC. Breast Cancer Res Treat 124 259-264 (2010)
- Substitution of aspartic acid with glutamic acid at position 67 of the BRCA1 RING domain retains ubiquitin ligase activity and zinc(II) binding with a reduced transition temperature. Atipairin A, Canyuk B, Ratanaphan A. J Biol Inorg Chem 16 217-226 (2011)
- Targeted substrate degradation by an engineered double RING ubiquitin ligase. Oyake D, Nishikawa H, Koizuka I, Fukuda M, Ohta T. Biochem Biophys Res Commun 295 370-375 (2002)
- A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125. Bijlmakers MJ, Teixeira JM, Boer R, Mayzel M, Puig-Sàrries P, Karlsson G, Coll M, Pons M, Crosas B. Sci Rep 6 29232 (2016)
- DNA breakpoint assay reveals a majority of gross duplications occur in tandem reducing VUS classifications in breast cancer predisposition genes. Richardson ME, Chong H, Mu W, Conner BR, Hsuan V, Willett S, Lam S, Tsai P, Pesaran T, Chamberlin AC, Park MS, Gray P, Karam R, Elliott A. Genet Med 21 683-693 (2019)
- Structure of the yeast Bre1 RING domain. Kumar P, Kumar P, Wolberger C. Proteins 83 1185-1190 (2015)
- The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function. Tembe V, Martino-Echarri E, Marzec KA, Mok MT, Brodie KM, Mills K, Lei Y, DeFazio A, Rizos H, Kettle E, Boadle R, Henderson BR. Cell Signal 27 1763-1771 (2015)
- BRCA1 and BRCA2 in breast cancer predisposition and recombination control. Scully R, Xie A. J Mammary Gland Biol Neoplasia 9 237-246 (2004)
- In Vitro Enhanced Sensitivity to Cisplatin in D67Y BRCA1 RING Domain Protein. Atipairin A, Ratanaphan A. Breast Cancer (Auckl) 5 201-208 (2011)
- Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress. Gilmore BL, Liang Y, Winton CE, Patel K, Karageorge V, Varano AC, Dearnaley W, Sheng Z, Kelly DF. Sci Rep 7 43435 (2017)
- Oncoviruses Can Drive Cancer by Rewiring Signaling Pathways Through Interface Mimicry. Guven-Maiorov E, Tsai CJ, Nussinov R. Front Oncol 9 1236 (2019)
- Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α. Ma Y, Tomita Y, Preet A, Clarke R, Englund E, Grindrod S, Nathan S, De Oliveira E, Brown ML, Rosen EM. Mol Endocrinol 28 1971-1986 (2014)
- Letter The RING domain of RING Finger 11 (RNF11) protein binds Ubc13 and inhibits formation of polyubiquitin chains. Budhidarmo R, Zhu J, Middleton AJ, Day CL. FEBS Lett 592 1434-1444 (2018)
- BARD1 germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma. Randall MP, Egolf LE, Vaksman Z, Samanta M, Tsang M, Groff D, Evans JP, Rokita JL, Layeghifard M, Shlien A, Maris JM, Diskin SJ, Bosse KR. J Natl Cancer Inst 116 138-148 (2024)
- Conservation of inter-protein binding sites in RUSH and RFBP, an ATP11B isoform. Hewetson A, Wright-Pastusek AE, Helmer RA, Wesley KA, Chilton BS. Mol Cell Endocrinol 292 79-86 (2008)
- Low concentrations of antimony impair DNA damage signaling and the repair of radiation-induced DSB in HeLa S3 cells. Koch B, Maser E, Hartwig A. Arch Toxicol 91 3823-3833 (2017)
- Primary structure-based function characterization of BRCT domain replicates in BRCA1. Chen Y, Borowicz S, Fackenthal J, Collart FR, Myatt E, Moy S, Babnigg G, Wilton R, Boernke WE, Schiffer M, Stevens FJ, Olopade OI. Biochem Biophys Res Commun 345 188-196 (2006)
- "Ring-fencing" BRCA1 tumor suppressor activity. Patel KJ, Crossan GP, Hodskinson MR. Cancer Cell 20 693-695 (2011)
- Alteration of radiation-sensitive processes associated with cancer and longevity by dietary 2-mercaptoethanol. Click RE. J Cancer Res Ther 10 127-132 (2014)
- Functional investigation of the BRCA1 Val1714Gly and Asp1733Gly variants by computational tools and yeast transcription activation assay. Yadegari F, Farahmand L, Esmaeili R, Samadi T, Majidzadeh K. Mol Biol Res Commun 8 113-118 (2019)
- Identification of a novel mutations BRCA1*c.80 + 3del4 and BRCA2*c.6589delA in Slovak HBOC families. Konecny M, Vizvaryova M, Zavodna K, Behulova R, Gerykova Bujalkova M, Krivulcik T, Cisarik F, Kausitz J, Weismanova E. Breast Cancer Res Treat 119 233-237 (2010)
- Multimodal approach to explore the pathogenicity of BARD1, ARG 658 CYS, and ILE 738 VAL mutants. Choudhary RK, Vikrant, Siddiqui QM, Thapa PS, Raikundalia S, Gadewal N, Kumar NS, Hosur MV, Varma AK. J Biomol Struct Dyn 34 1533-1544 (2016)
- Solution NMR structure of the TRIM21 B-box2 and identification of residues involved in its interaction with the RING domain. Wallenhammar A, Anandapadamanaban M, Lemak A, Mirabello C, Lundström P, Wallner B, Sunnerhagen M. PLoS One 12 e0181551 (2017)
- The Lotus japonicus Ubiquitin Ligase SIE3 Interacts With the Transcription Factor SIP1 and Forms a Homodimer. Feng Y, Wu P, Fu W, Peng L, Zhu H, Cao Y, Zhou X, Hong Z, Zhang Z, Yuan S. Front Plant Sci 11 795 (2020)
- The isolated N terminus of Ring1B is a well-folded, monomeric fragment with native-like structure. Martínez-Gómez AI, Villegas S, Aguado-Llera D, Bacarizo J, Cámara-Artigas A, Vidal M, Neira JL. Protein Eng Des Sel 27 1-11 (2014)
- The unique N-terminal zinc finger of synaptotagmin-like protein 4 reveals FYVE structure. Miyamoto K, Nakatani A, Saito K. Protein Sci 26 2451-2457 (2017)
- BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation. Witus SR, Tuttle LM, Li W, Zelter A, Wang M, Kermoade KE, Wilburn DB, Davis TN, Brzovic PS, Zhao W, Klevit RE. EMBO J 42 e113565 (2023)
- Computed cancer interactome explains the effects of somatic mutations in cancers. Zhang J, Pei J, Durham J, Bos T, Cong Q. Protein Sci 31 e4479 (2022)
- Correcting errors in the BRCA1 warning system. Liang Y, Dearnaley WJ, Alden NA, Solares MJ, Gilmore BL, Pridham KJ, Varano AC, Sheng Z, Alli E, Kelly DF. DNA Repair (Amst) 73 120-128 (2019)
- High-throughput PRIME-editing screens identify functional DNA variants in the human genome. Ren X, Yang H, Nierenberg JL, Sun Y, Chen J, Beaman C, Pham T, Nobuhara M, Takagi MA, Narayan V, Li Y, Ziv E, Shen Y. Mol Cell 83 4633-4645.e9 (2023)
- In silico analysis identifies a C3HC4-RING finger domain of a putative E3 ubiquitin-protein ligase located at the C-terminus of a polyglutamine-containing protein. Scior T, Luna F, Koch W, Sánchez-Ruiz JF. Braz J Med Biol Res 40 293-299 (2007)
- Overexpression of BRCA1 attenuates the sensitivity of PC9 cells to gefitinib. Feng W, Deng Y, Wu J, Zhang H, Liang J, Xian H, Yang S. Int J Clin Exp Pathol 8 12869-12876 (2015)
- SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation. Minten EV, Kapoor-Vazirani P, Li C, Zhang H, Balakrishnan K, Yu DS. Cell Rep 34 108921 (2021)
- Solution structure of the zinc finger domain of human RNF144A ubiquitin ligase. Miyamoto K, Migita K, Saito K. Protein Sci 29 1836-1842 (2020)
- The zinc finger domain of RING finger protein 141 reveals a unique RING fold. Miyamoto K, Uechi A, Saito K. Protein Sci 26 1681-1686 (2017)
- BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes. Burdett H, Foglizzo M, Musgrove LJ, Kumar D, Clifford G, Campbell LJ, Heath GR, Zeqiraj E, Wilson MD. Nucleic Acids Res 51 11080-11103 (2023)
- Biochemical characterization of TRIM72 E3 ligase and its interaction with the insulin receptor substrate 1. Gupta I, Dharadhar S, Sixma T, Khan S. Biochem Biophys Rep 21 100729 (2020)
- Biophysical evaluation to categorize pathogenicity of cancer-predisposing mutations identified in the BARD1 BRCT domain. Choudhary RK, Siddiqui MQ, Gadewal N, Kumar NS, Kuligina ES, Varma AK. RSC Adv 8 34056-34068 (2018)
- CRL4-DCAF8L1 Regulates BRCA1 and BARD1 Protein Stability. Liu F, Han Q, Zhang T, Chang F, Deng J, Huang X, Wang W, Xu Y, Li Q, Xu L, Zhang B, Li W, Li L, Su Y, Li Y, Shao G. Int J Biol Sci 18 1434-1450 (2022)
- Comprehensive evaluation and efficient classification of BRCA1 RING domain missense substitutions. Clark KA, Paquette A, Tao K, Bell R, Boyle JL, Rosenthal J, Snow AK, Stark AW, Thompson BA, Unger J, Gertz J, Varley KE, Boucher KM, Goldgar DE, Foulkes WD, Thomas A, Tavtigian SV. Am J Hum Genet 109 1153-1174 (2022)
- Critical role of cysteine-266 of SIE3 in regulating the ubiquitination and degradation of SIP1 transcription factor in Lotus japonicus. Wu P, Feng Y, Zou Z, Cao Y, Yuan S. Planta 253 126 (2021)
- Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair. Wang M, Li W, Tomimatsu N, Yu CH, Ji JH, Alejo S, Witus SR, Alimbetov D, Fitzgerald O, Wu B, Wang Q, Huang Y, Gan Y, Dong F, Kwon Y, Sareddy GR, Curiel TJ, Habib AA, Hromas R, Dos Santos Passos C, Yao T, Ivanov DN, Brzovic PS, Burma S, Klevit RE, Zhao W. Mol Cell 83 3679-3691.e8 (2023)
- Differential Expression of BARD1 Isoforms in Melanoma. McDougall LI, Powell RM, Ratajska M, Lynch-Sutherland CF, Hossain SM, Wiggins GAR, Harazin-Lechowska A, Cybulska-Stopa B, Motwani J, Macaulay EC, Reid G, Walker LC, Ryś J, Eccles MR. Genes (Basel) 12 (2021)
- Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line. Li Q, Kaur A, Okada K, McKenney RJ, Engebrecht J. PLoS Genet 19 e1010457 (2023)
- Impact of a Single Nucleotide Polymorphism on the 3D Protein Structure and Ubiquitination Activity of E3 Ubiquitin Ligase Arkadia. Birkou M, Raptis V, Marousis KD, Tsevis A, Bourikas K, Bentrop D, Episkopou V, Spyroulias GA. Front Mol Biosci 9 844129 (2022)
- In-Silico Analyses of Nonsynonymous Variants in the BRCA1 Gene. Arshad S, Ishaque I, Mumtaz S, Rashid MU, Malkani N. Biochem Genet 59 1506-1526 (2021)
- RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination. Zhu Q, Huang J, Huang H, Li H, Yi P, Kloeber JA, Yuan J, Chen Y, Deng M, Luo K, Gao M, Guo G, Tu X, Yin P, Zhang Y, Su J, Chen J, Lou Z. Nat Commun 12 6653 (2021)
- Refinement of the assignment to the ACMG/AMP BS3 and PS3 criteria of eight BRCA1 variants of uncertain significance by integrating available functional data with protein interaction assays. Caleca L, Radice P. Front Oncol 13 1146604 (2023)
- Simulation and Computational Study of RING Domain Mutants of BRCA1 and Ube2k in AD/PD Pathophysiology. Sahu M, Rani N, Kumar P. Mol Biotechnol (2024)
- Solution structure of the PHD finger from the human KIAA1045 protein. Miyamoto K, Yamashita A, Saito K. Protein Sci 27 987-992 (2018)
- Structure of the nutrient-sensing hub GATOR2. Valenstein ML, Rogala KB, Lalgudi PV, Brignole EJ, Gu X, Saxton RA, Chantranupong L, Kolibius J, Quast JP, Sabatini DM. Nature 607 610-616 (2022)
- The BRCA1/BARD1 complex recognizes pre-ribosomal RNA to facilitate homologous recombination. Wu D, Huang H, Chen T, Gai X, Li Q, Wang C, Yao J, Liu Y, Cai S, Yu X. Cell Discov 9 99 (2023)
- The dependence of the risk of breast cancer in women on their genotype. Tarasov VA, Aslanyan MM, Tsyrendorzhieva ES, Gar'kavtseva RF, Lyubchenko LN, Altukhov YP. Dokl Biol Sci 398 391-394 (2004)
- Unique RING finger structure from the human HRD1 protein. Miyamoto K, Taguchi Y, Saito K. Protein Sci 28 448-453 (2019)