PDBe 1j38

X-ray diffraction
2.6Å resolution

Crystal Structure of Drosophila AnCE


Function and Biology Details

Reaction catalysed:
Release of a C-terminal dipeptide, oligopeptide-|-Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor activity, but no action on angiotensin II.
Biochemical function:
Biological process:
Cellular component:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Angiotensin-converting enzyme Chains: A, B
Molecule details ›
Chains: A, B
Length: 607 amino acids
Theoretical weight: 70.44 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera frugiperda
  • Canonical: Q10714 (Residues: 14-615; Coverage: 100%)
Gene names: Ance, CG8827, Race
Sequence domains: Angiotensin-converting enzyme

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P21
Unit cell:
a: 94.912Å b: 121.223Å c: 94.74Å
α: 90° β: 99.39° γ: 90°
R R work R free
0.246 0.246 0.281
Expression system: Spodoptera frugiperda