PDBe 1izb

X-ray diffraction
2Å resolution

ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero 12-mer
hetero hexamer
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Best match: P01315 (Residues: 88-108)
Gene name: INS
Insulin B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Best match: P01315 (Residues: 25-53)
Gene name: INS

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: R3
Unit cell:
a: 82.85Å b: 82.85Å c: 34.1Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 not available not available
Expression system: Not provided