› 1iy2

X-ray diffraction
3.2Å resolution

Crystal structure of the FtsH ATPase domain from Thermus thermophilus

Released:
DOI: 10.2210/pdb1iy2/pdb
PDB entry 1iy2 coloured by chain, front view.
PDB entry 1iy2 coloured by chain, side view.
PDB entry 1iy2 coloured by chain, top view.
Source organism: Thermus thermophilus
Primary publication:
Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8.
Niwa H, Tsuchiya D, Makyio H, Yoshida M, Morikawa K
Structure 10 1415-23 (2002)
PMID: 12377127

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177940 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent zinc metalloprotease FtsH Chain: A
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 29.94 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5SI82 (Residues: 126-393; Coverage: 43%)
Gene names: TTHA1492, ftsH
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MACSCIENCE
Spacegroup: C2221
Unit cell:
a: 86.647Å b: 101.149Å c: 66.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.253 0.253 0.294
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

Evolutionary relationships and structural mechanisms of AAA+ proteins.
Erzberger et al. (2006)
14 more

2 mentions without citation

SymmRef: a flexible refinement method for symmetric multimers.
Mashiach-Farkash et al. (2011)
1 more