PDBe 1isr

X-ray diffraction
4Å resolution

Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Metabotropic glutamate receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 490 amino acids
Theoretical weight: 55.26 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
  • Canonical: P23385 (Residues: 33-522; Coverage: 42%)
Gene names: Gprc1a, Grm1, Mglur1
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL40B2
Spacegroup: P3221
Unit cell:
a: 145.348Å b: 145.348Å c: 76.754Å
α: 90° β: 90° γ: 120°
R R work R free
0.238 0.237 0.259
Expression system: Spodoptera frugiperda