Function and Biology

Crystal Structure of the MRP14 complexed with CHAPS

Source organism: Homo sapiens
Biochemical function: RAGE receptor binding
Biological process: positive regulation of intrinsic apoptotic signaling pathway
Cellular component: S100A9 complex

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF01023
Domain description: S-100/ICaBP type calcium binding domain
Occurring in:
  1. Protein S100-A9
The deposited structure of PDB entry 1irj contains 8 copies of Pfam domain PF01023 (S-100/ICaBP type calcium binding domain) in Protein S100-A9. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002048
Domain description: EF-hand domain
Occurring in:
  1. Protein S100-A9
IPR013787
Domain description: S100/CaBP-9k-type, calcium binding, subdomain
Occurring in:
  1. Protein S100-A9
IPR018247
Domain description: EF-Hand 1, calcium-binding site
Occurring in:
  1. Protein S100-A9
IPR001751
Domain description: S100/Calcium binding protein 7/8-like, conserved site
Occurring in:
  1. Protein S100-A9
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Protein S100-A9

Structure domain

CATH CATH domain
1.10.238.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Recoverin; domain 1
Homology: EF-hand
Occurring in:
  1. Protein S100-A9
The deposited structure of PDB entry 1irj contains 8 copies of CATH domain 1.10.238.10 (Recoverin; domain 1) in Protein S100-A9. Showing 1 copy in chain A.
SCOP SCOP annotation
47478
Class: All alpha proteins
Fold: EF Hand-like
Superfamily: EF-hand
Occurring in:
  1. Protein S100-A9
The deposited structure of PDB entry 1irj contains 8 copies of SCOP domain 47478 (S100 proteins) in Protein S100-A9. Showing 1 copy in chain A.