PDBe 1imo

Solution NMR

NMR STRUCTURE OF HUMAN DNA LIGASE IIIALPHA BRCT DOMAIN

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
(1a) ATP + [DNA ligase]-L-lysine = [DNA ligase]-N(6)-(5'-adenylyl)-L-lysine + diphosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA ligase 3 Chain: A
Molecule details ›
Chain: A
Length: 88 amino acids
Theoretical weight: 9.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49916 (Residues: 924-1009; Coverage: 9%)
Gene name: LIG3
Sequence domains: DNA ligase 3 BRCT domain
Structure domains: BRCT domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, torsion angle dynamics
Expression system: Escherichia coli