PDBe 1ilp

Solution NMR

CXCR-1 N-TERMINAL PEPTIDE BOUND TO INTERLEUKIN-8

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
C-X-C chemokine receptor type 1 Chain: C
Molecule details ›
Chain: C
Length: 18 amino acids
Theoretical weight: 2.07 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P25024 (Residues: 9-29; Coverage: 5%)
Gene names: CMKAR1, CXCR1, IL8RA
Interleukin-8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 72 amino acids
Theoretical weight: 8.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P10145 (Residues: 28-99; Coverage: 91%)
Gene names: CXCL8, IL8
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED MOLECULAR DYNAMICS
Expression systems:
  • Not provided
  • Escherichia coli K-12