PDBe 1ijx

X-ray diffraction
1.9Å resolution

CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF SECRETED FRIZZLED-RELATED PROTEIN 3 (SFRP-3;FZB)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Secreted frizzled-related protein 3 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 127 amino acids
Theoretical weight: 14.2 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P97401 (Residues: 33-157; Coverage: 43%)
Gene names: Fiz, Fre, Frzb, Frzb1, Sfrp3
Sequence domains: Fz domain
Structure domains: Frizzled cysteine-rich domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P21
Unit cell:
a: 96.05Å b: 48.69Å c: 83.31Å
α: 90° β: 90.8° γ: 90°
R-values:
R R work R free
0.22 0.22 0.257
Expression system: Cricetulus griseus