Function and Biology

Structure of the C-domain of Human Cardiac Troponin C in Complex with Ca2+ Sensitizer EMD 57033

Source organism: Homo sapiens
Biochemical function: calcium ion binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF13499
Domain description: EF-hand domain pair
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
The deposited structure of PDB entry 1ih0 contains 1 copy of Pfam domain PF13499 (EF-hand domain pair) in Troponin C, slow skeletal and cardiac muscles. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002048
Domain description: EF-hand domain
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
IPR018247
Domain description: EF-Hand 1, calcium-binding site
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles

Structure domain

CATH CATH domain
1.10.238.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Recoverin; domain 1
Homology: EF-hand
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
The deposited structure of PDB entry 1ih0 contains 1 copy of CATH domain 1.10.238.10 (Recoverin; domain 1) in Troponin C, slow skeletal and cardiac muscles. Showing 1 copy in chain A.
SCOP SCOP annotation
47502
Class: All alpha proteins
Fold: EF Hand-like
Superfamily: EF-hand
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
The deposited structure of PDB entry 1ih0 contains 1 copy of SCOP domain 47502 (Calmodulin-like) in Troponin C, slow skeletal and cardiac muscles. Showing 1 copy in chain A.