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Crystal Structure of Yeast Hexokinase PII with the correct amino acid sequence

X-ray diffraction
2.2Å resolution
PDB entry 1ig8 coloured by chain, front view.
PDB entry 1ig8 coloured by chain, side view.
PDB entry 1ig8 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Hexokinase-2
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Multimeric state: monomeric
Accessible surface area: 19990.74 Å2
Buried surface area: 159.13 Å2
Dissociation area: 79.57 Å2
Dissociation energy (ΔGdiss): 13.18 kcal/mol
Dissociation entropy (TΔSdiss): 0.63 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138189

Macromolecules

Hexokinase-2
Chain: A
Length: 486 amino acids
Theoretical weight: 54 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P04807 (Residues: 1-486; Coverage: 100%)
Gene names: HEX1, HKB, HXK2, NRB486, YGL253W
Pfam:
InterPro:
CATH:
SCOP: Hexokinase
Hexokinase-2 in PDB entry 1ig8, assembly 1, front view.
Hexokinase-2 in PDB entry 1ig8, assembly 1, side view.
Hexokinase-2 in PDB entry 1ig8, assembly 1, top view.
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