PDBe 1ig7

X-ray diffraction
2.2Å resolution

Msx-1 Homeodomain/DNA Complex Structure

Primary publication:
Crystal structure of the Msx-1 homeodomain/DNA complex.
Biochemistry 40 12013-21 (2001)
PMID: 11580277

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Homeobox protein MSX-1 Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.94 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P13297 (Residues: 173-230; Coverage: 19%)
Gene names: Hox7, Hox7.1, Msx1
Sequence domains: Homeobox domain
Structure domains: Homeodomain-like
5'-D(*CP*AP*CP*TP*AP*AP*TP*TP*GP*AP*AP*GP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 13 nucleotides
Theoretical weight: 4 KDa
Source organism: Synthetic construct
Expression system: Not provided
Molecule details ›
Chain: C
Length: 16 nucleotides
Theoretical weight: 4.85 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 33.6Å b: 60.96Å c: 82.3Å
α: 90° β: 90° γ: 90°
R R work R free
0.212 0.205 0.274
Expression systems:
  • Escherichia coli
  • Not provided