Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138509 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-4
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Interleukin 4
Structure domains: Growth Hormone; Chain: A;
Length: 129 amino acids
Theoretical weight: 14.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P05112 (Residues: 25-153; Coverage: 100%)
Sequence domains: Interleukin 4
Structure domains: Growth Hormone; Chain: A;
Soluble interleukin-4 receptor subunit alpha
Molecule details ›
Chain: B
Length: 207 amino acids
Theoretical weight: 23.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Interleukin-4 receptor alpha chain, N-terminal
Structure domains: Immunoglobulins
Length: 207 amino acids
Theoretical weight: 23.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P24394 (Residues: 26-232; Coverage: 26%)
Sequence domains: Interleukin-4 receptor alpha chain, N-terminal
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup:
P212121
Expression system: Escherichia coli
