PDBe 1i8h

Solution NMR

SOLUTION STRUCTURE OF PIN1 WW DOMAIN COMPLEXED WITH HUMAN TAU PHOSPHOTHREONINE PEPTIDE

Released:

Function and Biology Details

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0). 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Microtubule-associated protein tau Chain: A
Molecule details ›
Chain: A
Length: 13 amino acids
Theoretical weight: 1.46 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10636 (Residues: 542-554; Coverage: 2%)
Gene names: MAPT, MAPTL, MTBT1, TAU
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Chain: B
Molecule details ›
Chain: B
Length: 39 amino acids
Theoretical weight: 4.46 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13526 (Residues: 6-44; Coverage: 24%)
Gene name: PIN1
Sequence domains: WW domain

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Not provided