PDBe 1i7x

X-ray diffraction
3Å resolution

BETA-CATENIN/E-CADHERIN COMPLEX

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Catenin beta-1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 538 amino acids
Theoretical weight: 58.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02248 (Residues: 134-671; Coverage: 69%)
Gene names: Catnb, Ctnnb1
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant
E-Cad/CTF2 Chains: B, D
Molecule details ›
Chains: B, D
Length: 151 amino acids
Theoretical weight: 17 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P09803 (Residues: 734-884; Coverage: 18%)
Gene name: Cdh1
Sequence domains: Cadherin cytoplasmic region
Structure domains: TCF3-CBD (Catenin binding domain)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: C2
Unit cell:
a: 180.8Å b: 134.2Å c: 94.2Å
α: 90° β: 94.3° γ: 90°
R-values:
R R work R free
0.2 0.196 0.242
Expression system: Escherichia coli