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CRYSTAL STRUCTURE OF RNASE III ENDONUCLEASE DOMAIN FROM AQUIFEX AEOLICUS AT 2.15 ANGSTROM RESOLUTION

Source organism: Aquifex aeolicus
Biochemical function: ribonuclease III activity
Biological process: RNA processing
Cellular component: not assigned

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EC 3.1.26.3: Ribonuclease III

Reaction catalysed:
Endonucleolytic cleavage to 5'-phosphomonoester.
Systematic name:
-
Alternative Name(s):
  • RNase III
  • Ribonuclease 3

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00636
Domain description: Ribonuclease III domain
Occurring in:
  1. Ribonuclease 3
The deposited structure of PDB entry 1i4s contains 2 copies of Pfam domain PF00636 (Ribonuclease III domain) in Ribonuclease 3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000999
Domain description: Ribonuclease III domain
Occurring in:
  1. Ribonuclease 3
IPR036389
Domain description: Ribonuclease III, endonuclease domain superfamily
Occurring in:
  1. Ribonuclease 3

Structure domain

CATH CATH domain
1.10.1520.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Ribonuclease iii, N-terminal Endonuclease Domain; Chain A
Homology: Ribonuclease III domain
Occurring in:
  1. Ribonuclease 3
The deposited structure of PDB entry 1i4s contains 2 copies of CATH domain 1.10.1520.10 (Ribonuclease iii, N-terminal Endonuclease Domain; Chain A) in Ribonuclease 3. Showing 1 copy in chain A.
SCOP SCOP annotation
69066
Class: All alpha proteins
Fold: RNase III domain-like
Superfamily: RNase III domain-like
Occurring in:
  1. Ribonuclease 3
The deposited structure of PDB entry 1i4s contains 2 copies of SCOP domain 69066 (RNase III catalytic domain-like) in Ribonuclease 3. Showing 1 copy in chain A.

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