PDBe 1hz8

Solution NMR

SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A CONCATEMER OF EGF-HOMOLOGY MODULES OF THE HUMAN LOW DENSITY LIPOPROTEIN RECEPTOR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Low-density lipoprotein receptor Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01130 (Residues: 314-395; Coverage: 10%)
Gene name: LDLR
Sequence domains: Complement Clr-like EGF-like
Structure domains: Laminin

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: 1. Torsion angles dynamics 2. Restrained molecular dynamics with calcium 3. Energy minimisation
Expression system: Escherichia coli