PDBe 1hug

X-ray diffraction
2Å resolution

Differences in anionic inhibition of Human Carbonic Anhydrase I revealed from the structures of iodide and gold cyanide inhibitor complexes

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 1 Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 28.77 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Best match: P00915 (Residues: 2-261)
Gene name: CA1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 81.8Å b: 75.2Å c: 37.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 not available not available
Expression system: Not provided