PDBe 1hkx

X-ray diffraction
2.65Å resolution

Crystal structure of calcium/calmodulin-dependent protein kinase


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo 14-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Calcium/calmodulin-dependent protein kinase type II subunit alpha Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Length: 147 amino acids
Theoretical weight: 16.88 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P11798 (Residues: 336-478; Coverage: 30%)
Gene name: Camk2a
Sequence domains: Calcium/calmodulin dependent protein kinase II association domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2, ALS BEAMLINE 8.2.1
Spacegroup: C2
Unit cell:
a: 147.946Å b: 118.043Å c: 157.82Å
α: 90° β: 110.91° γ: 90°
R R work R free
0.246 0.246 0.279
Expression system: Escherichia coli BL21(DE3)