› 1his

Solution NMR

Structure and dynamics of des-pentapeptide-insulin in solution: the molten-globule hypothesis.

Released:
DOI: 10.2210/pdb1his/pdb
PDB entry 1his coloured by chain, ensemble of 15 models, front view.
PDB entry 1his coloured by chain, ensemble of 15 models, side view.
PDB entry 1his coloured by chain, ensemble of 15 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure and dynamics of des-pentapeptide-insulin in solution: the molten-globule hypothesis.
Hua QX, Kochoyan M, Weiss MA
Proc Natl Acad Sci U S A 89 2379-83 (1992)
PMID: 1549601

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134182 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Gene name: INS
Insulin B chain Chain: B
Molecule details ›
Chain: B
Length: 25 amino acids
Theoretical weight: 2.84 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 25-49; Coverage: 29%)
Gene name: INS

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

6 review citations

Principles of protein folding--a perspective from simple exact models.
Dill et al. (1995)
5 more

31 mentions without citation

Were there any "misassignments" among iron-sulfur clusters N4, N5 and N6b in NADH-quinone oxidoreductase (complex I)?
Ohnishi et al. (2008)
30 more