PDBe 1h9u

X-ray diffraction
2.7Å resolution

The structure of the human retinoid-X-receptor beta ligand binding domain in complex with the specific synthetic agonist LG100268


Function and Biology Details

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Retinoic acid receptor RXR-beta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 224 amino acids
Theoretical weight: 24.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P28702 (Residues: 299-522; Coverage: 42%)
Gene names: NR2B2, RXRB
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2
Unit cell:
a: 123.886Å b: 106.882Å c: 100.587Å
α: 90° β: 122.56° γ: 90°
R R work R free
0.273 0.273 0.306
Expression system: Escherichia coli BL21(DE3)