› 1h6u

X-ray diffraction
1.8Å resolution

Internalin H: crystal structure of fused N-terminal domains.

Released:
DOI: 10.2210/pdb1h6u/pdb
PDB entry 1h6u coloured by chain, front view.
PDB entry 1h6u coloured by chain, side view.
PDB entry 1h6u coloured by chain, top view.
Source organism: Listeria monocytogenes
Primary publication:
Internalins from the human pathogen Listeria monocytogenes combine three distinct folds into a contiguous internalin domain.
Schubert WD, Göbel G, Diepholz M, Darji A, Kloer D, Hain T, Chakraborty T, Wehland J, Domann E, Heinz DW
J Mol Biol 312 783-94 (2001)
PMID: 11575932

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195627 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Class 1 internalin InlH Chain: A
Molecule details ›
Chain: A
Length: 308 amino acids
Theoretical weight: 32.59 KDa
Source organism: Listeria monocytogenes
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9ZEY1 (Residues: 36-343; Coverage: 56%)
Gene names: FJL03_05090, inlH
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: I212121
Unit cell:
a: 57.481Å b: 100.682Å c: 119.931Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.167 0.217
Expression system: Escherichia coli BL21

Quick links

Citations

15 review citations

Leucine-rich repeats and pathogen recognition in Toll-like receptors.
Bell et al. (2003)
14 more

4 mentions without citation

TBCE Mutations Cause Early-Onset Progressive Encephalopathy with Distal Spinal Muscular Atrophy.
Sferra et al. (2016)
3 more