PDBe 1h59

X-ray diffraction
2.1Å resolution

Complex of IGFBP-5 with IGF-I

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin-like growth factor I Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 7.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P05019 (Residues: 49-118; Coverage: 40%)
Gene names: IBP1, IGF1
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like
Insulin-like growth factor-binding protein 5 Chain: B
Molecule details ›
Chain: B
Length: 54 amino acids
Theoretical weight: 6.05 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P24593 (Residues: 59-112; Coverage: 21%)
Gene names: IBP5, IGFBP5
Structure domains: Omega-AgatoxinV

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P213
Unit cell:
a: 74.385Å b: 74.385Å c: 74.385Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.218 0.262