PDBe 1h3w

X-ray diffraction
2.85Å resolution

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin heavy constant gamma 1 Chain: M
Molecule details ›
Chain: M
Length: 223 amino acids
Theoretical weight: 25.13 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01857 (Residues: 108-330; Coverage: 68%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2221
Unit cell:
a: 49.55Å b: 149.25Å c: 75.75Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.279 0.279 0.32