PDBe 1h3h

Solution NMR

Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
GRB2-related adaptor protein 2 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 6.95 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O89100 (Residues: 263-322; Coverage: 19%)
Gene names: Gads, Grap2, Grb2l, Grid, Mona
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Lymphocyte cytosolic protein 2 Chain: B
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13094 (Residues: 232-241; Coverage: 2%)
Gene name: LCP2

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: MDSA
Expression system: Escherichia coli BL21(DE3)