PDBe 1gzr

X-ray diffraction
2Å resolution

Human Insulin-like growth factor; ESRF data


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Insulin-like growth factor I Chain: B
Molecule details ›
Chain: B
Length: 70 amino acids
Theoretical weight: 7.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P05019 (Residues: 49-118; Coverage: 40%)
Gene names: IBP1, IGF1
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2221
Unit cell:
a: 30.777Å b: 69.468Å c: 65.003Å
α: 90° β: 90° γ: 90°
R R work R free
0.24 0.237 0.295
Expression system: Escherichia coli