PDBe 1gwz

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTEIN TYROSINE PHOSPHATASE SHP-1

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1.
J. Biol. Chem. 273 28199-207 (1998)
PMID: 9774441

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase non-receptor type 6 Chain: A
Molecule details ›
Chain: A
Length: 299 amino acids
Theoretical weight: 34.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P29350 (Residues: 243-541)
Gene names: HCP, PTP1C, PTPN6

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21
Unit cell:
a: 41.82Å b: 87.78Å c: 43Å
α: 90° β: 117.4° γ: 90°
R-values:
R R work R free
0.209 0.209 0.293
Expression system: Escherichia coli