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Structure of human chitotriosidase

X-ray diffraction
2.35Å resolution
PDB entry 1guv coloured by chain, front view.
PDB entry 1guv coloured by chain, side view.
PDB entry 1guv coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Chitotriosidase-1
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Multimeric state: monomeric
Accessible surface area: 14394.45 Å2
Buried surface area: 1739.01 Å2
Dissociation area: 100.87 Å2
Dissociation energy (ΔGdiss): -2.03 kcal/mol
Dissociation entropy (TΔSdiss): -0.39 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-171609

Macromolecules

Chitotriosidase-1
Chain: A
Length: 366 amino acids
Theoretical weight: 40.9 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q13231 (Residues: 22-387; Coverage: 82%)
Gene name: CHIT1
Pfam: Glycosyl hydrolases family 18
InterPro:
CATH:
SCOP:
Chitotriosidase-1 in PDB entry 1guv, assembly 1, front view.
Chitotriosidase-1 in PDB entry 1guv, assembly 1, side view.
Chitotriosidase-1 in PDB entry 1guv, assembly 1, top view.
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