PDBe 1guf

X-ray diffraction
2.25Å resolution

Enoyl thioester reductase from Candida tropicalis

Released:

Function and Biology Details

Reaction catalysed:
An acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl- carrier protein] + NADPH. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 364 amino acids
Theoretical weight: 39.56 KDa
Source organism: Candida tropicalis
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q8WZM3 (Residues: 23-386; Coverage: 94%)
Gene name: ETR1
Sequence domains: Zinc-binding dehydrogenase
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: P3121
Unit cell:
a: 92.17Å b: 92.17Å c: 225.66Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.178 0.215
Expression system: Saccharomyces cerevisiae