PDBe 1gqm

X-ray diffraction
2.7Å resolution

The structure of S100A12 in a hexameric form and its proposed role in receptor signalling

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-A12 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 91 amino acids
Theoretical weight: 10.46 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P80511 (Residues: 2-92; Coverage: 99%)
Gene name: S100A12
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 53.875Å b: 100.501Å c: 112.687Å
α: 90° β: 94.55° γ: 90°
R-values:
R R work R free
0.219 0.217 0.281