PDBe 1gqg

X-ray diffraction
1.7Å resolution

Quercetin 2,3-dioxygenase in complex with the inhibitor diethyldithiocarbamate

Released:

Function and Biology Details

Reaction catalysed:
Quercetin + O(2) = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H(+). 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Quercetin 2,3-dioxygenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 350 amino acids
Theoretical weight: 37.96 KDa
Source organism: Aspergillus japonicus
Expression system: Aspergillus awamori
UniProt:
  • Canonical: Q7SIC2 (Residues: 1-350; Coverage: 100%)
Structure domains: Jelly Rolls

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P21
Unit cell:
a: 108.939Å b: 55.646Å c: 123.863Å
α: 90° β: 98.26° γ: 90°
R-values:
R R work R free
0.162 0.161 0.183
Expression system: Aspergillus awamori