› 1gnj

X-ray diffraction
2.6Å resolution

HUMAN SERUM ALBUMIN COMPLEXED WITH cis-5,8,11,14-EICOSATETRAENOIC ACID (ARACHIDONIC ACID)

Released:
DOI: 10.2210/pdb1gnj/pdb
PDB entry 1gnj coloured by chain, front view.
PDB entry 1gnj coloured by chain, side view.
PDB entry 1gnj coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of human serum albumin complexed with monounsaturated and polyunsaturated fatty acids.
Petitpas I, Grüne T, Bhattacharya AA, Curry S
J Mol Biol 314 955-60 (2001)
PMID: 11743713

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136176 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chain: A
Molecule details ›
Chain: A
Length: 585 amino acids
Theoretical weight: 66.57 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P02768 (Residues: 25-609; Coverage: 99%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Sequence domains: Serum albumin family
Structure domains: Serum Albumin; Chain A, Domain 1

Ligands and Environments

1 bound ligand:
Ligand ACD 8 x ACD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2
Unit cell:
a: 190.219Å b: 38.972Å c: 96.236Å
α: 90° β: 105.75° γ: 90°
R-values:
R R work R free
0.194 0.194 0.245
Expression system: Saccharomyces cerevisiae

Quick links

Citations

31 review citations

Practical aspects of the ligand-binding and enzymatic properties of human serum albumin.
Kragh-Hansen et al. (2002)
30 more

7 mentions without citation

Recent topics in chemical and clinical research on glycated albumin.
Ueda et al. (2015)
6 more