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Crystal Structure of Cys25Ser mutant of human cathepsin S

X-ray diffraction
2.2Å resolution
PDB entry 1glo coloured by chain, front view.
PDB entry 1glo coloured by chain, side view.
PDB entry 1glo coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Cathepsin S
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Multimeric state: monomeric
Accessible surface area: 9959.41 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-150575

Macromolecules

Cathepsin S
Chain: A
Length: 217 amino acids
Theoretical weight: 23.98 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P25774 (Residues: 115-331; Coverage: 69%)
Gene name: CTSS
Pfam: Papain family cysteine protease
InterPro:
CATH: Cysteine proteinases
SCOP: Papain-like
Cathepsin S in PDB entry 1glo, assembly 1, front view.
Cathepsin S in PDB entry 1glo, assembly 1, side view.
Cathepsin S in PDB entry 1glo, assembly 1, top view.
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