PDBe 1ggp

X-ray diffraction
2.7Å resolution

CRYSTAL STRUCTURE OF TRICHOSANTHES KIRILOWII LECTIN-1 AND ITS RELATION TO THE TYPE 2 RIBOSOME INACTIVATING PROTEINS

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
rRNA N-glycosidase Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 24.38 KDa
Source organism: Trichosanthes kirilowii
UniProt:
  • Canonical: Q7SIF0 (Residues: 1-234; Coverage: 100%)
Sequence domains: Ribosome inactivating protein
Structure domains:
Sugar binding protein Chain: B
Molecule details ›
Chain: B
Length: 254 amino acids
Theoretical weight: 26.65 KDa
Source organism: Trichosanthes kirilowii
UniProt:
  • Canonical: Q7SIF1 (Residues: 1-254; Coverage: 100%)
Sequence domains: Ricin-type beta-trefoil lectin domain
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 44.96Å b: 69.87Å c: 180.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.3