PDBe 1gec

X-ray diffraction
2.1Å resolution

GLYCYL ENDOPEPTIDASE-COMPLEX WITH BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE COVALENTLY BOUND TO CYSTEINE 25

Released:

Function and Biology Details

Reaction catalysed:
Preferential cleavage: Gly-|-Xaa, in proteins and in small molecule substrates. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Papaya proteinase 4 Chain: E
Molecule details ›
Chain: E
Length: 216 amino acids
Theoretical weight: 23.34 KDa
Source organism: Carica papaya
UniProt:
  • Canonical: P05994 (Residues: 133-348; Coverage: 66%)
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases
BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE INHIBITOR Chain: I
Molecule details ›
Chain: I
Length: 5 amino acids
Theoretical weight: 464 Da
Source organism: Synthetic construct
Expression system: Not provided
UniProt:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P31
Unit cell:
a: 55.78Å b: 55.78Å c: 64.43Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.196 0.196 0.258
Expression system: Not provided