PDBe 1g8i

X-ray diffraction
1.9Å resolution

CRYSTAL STRUCTURE OF HUMAN FREQUENIN (NEURONAL CALCIUM SENSOR 1)

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuronal calcium sensor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 190 amino acids
Theoretical weight: 21.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P62166 (Residues: 1-190; Coverage: 100%)
Gene names: FLUP, FREQ, NCS1
Sequence domains:
Structure domains: EF-hand

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21
Unit cell:
a: 53.811Å b: 55.524Å c: 77.705Å
α: 90° β: 94.25° γ: 90°
R-values:
R R work R free
0.22 0.22 0.263
Expression system: Escherichia coli BL21