PDBe 1g83

X-ray diffraction
2.6Å resolution

CRYSTAL STRUCTURE OF FYN SH3-SH2

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Fyn Chains: A, B
Molecule details ›
Chains: A, B
Length: 165 amino acids
Theoretical weight: 18.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P06241 (Residues: 82-246; Coverage: 31%)
  • Best match: P06241-3 (Residues: 82-232)
Gene name: FYN
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21
Unit cell:
a: 39.97Å b: 89.96Å c: 60.27Å
α: 90° β: 101.44° γ: 90°
R-values:
R R work R free
0.214 0.214 0.277
Expression system: Escherichia coli BL21