PDBe 1fyn

X-ray diffraction
2.3Å resolution

PHOSPHOTRANSFERASE

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
3BP-2 Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.03 KDa
Source organism: Unidentified
Expression system: Not provided
Tyrosine-protein kinase Fyn Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 6.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06241 (Residues: 81-142; Coverage: 12%)
Gene name: FYN
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I222
Unit cell:
a: 42Å b: 43.3Å c: 65.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.234 not available
Expression systems:
  • Not provided
  • Escherichia coli