PDBe 1fva

X-ray diffraction
1.7Å resolution

CRYSTAL STRUCTURE OF BOVINE METHIONINE SULFOXIDE REDUCTASE

Released:

Function and Biology Details

Reaction catalysed:
(1) Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L- methionine (S)-S-oxide + thioredoxin. (2) L-methionine + thioredoxin disulfide + H(2)O = L-methionine (S)-S- oxide + thioredoxin. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial peptide methionine sulfoxide reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 217 amino acids
Theoretical weight: 24.03 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P54149 (Residues: 13-229; Coverage: 93%)
Gene name: MSRA
Sequence domains: Peptide methionine sulfoxide reductase
Structure domains: Peptide methionine sulfoxide reductase

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P21
Unit cell:
a: 53.71Å b: 66.199Å c: 62.137Å
α: 90° β: 90.99° γ: 90°
R-values:
R R work R free
0.207 0.207 0.28
Expression system: Escherichia coli