PDBe 1fot

X-ray diffraction
2.8Å resolution

STRUCTURE OF THE UNLIGANDED CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT FROM SACCHAROMYCES CEREVISIAE

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
cAMP-dependent protein kinase type 1 Chain: A
Molecule details ›
Chain: A
Length: 318 amino acids
Theoretical weight: 37.41 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P06244 (Residues: 81-397; Coverage: 80%)
Gene names: J0541, PKA1, SRA3, TPK1, YJL164C
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P6522
Unit cell:
a: 61Å b: 61Å c: 322Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.194 0.243
Expression system: Saccharomyces cerevisiae