1fos Citations

Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.

Nature 373 257-61 (1995)
Cited: 320 times
EuropePMC logo PMID: 7816143

Abstract

The Fos and Jun families of eukaryotic transcription factors heterodimerize to form complexes capable of binding 5'-TGAGTCA-3' DNA elements. We have determined the X-ray crystal structure of a heterodimer of the bZIP regions of c-Fos and c-Jun bound to DNA. Both subunits form continuous alpha-helices. The carboxy-terminal regions form an asymmetric coiled-coil, and the amino-terminal regions make base-specific contacts with DNA in the major groove. Comparison of the two crystallographically distinct protein-DNA complexes show that the coiled-coil is flexibly joined to the basic regions and that the Fos-Jun heterodimer does not recognize the asymmetric 5'-TGAGTCA-3' recognition element in a unique orientation. There is an extensive network of electrostatic interactions between subunits within the coiled-coil, consistent with proposals that these interactions determine preferential formation of the heterodimer over either of the homodimers.

Reviews - 1fos mentioned but not cited (2)

  1. Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics. Paleček E, Tkáč J, Bartošík M, Bertók T, Ostatná V, Paleček J. Chem. Rev. 115 2045-2108 (2015)
  2. Redox regulation of DNA repair: implications for human health and cancer therapeutic development. Luo M, He H, Kelley MR, Georgiadis MM. Antioxid. Redox Signal. 12 1247-1269 (2010)

Articles - 1fos mentioned but not cited (13)

  1. Finding nuclear localization signals. Cokol M, Nair R, Rost B. EMBO Rep. 1 411-415 (2000)
  2. Quantitative parameters for amino acid-base interaction: implications for prediction of protein-DNA binding sites. Mandel-Gutfreund Y, Margalit H. Nucleic Acids Res. 26 2306-2312 (1998)
  3. A conserved trimerization motif controls the topology of short coiled coils. Kammerer RA, Kostrewa D, Progias P, Honnappa S, Avila D, Lustig A, Winkler FK, Pieters J, Steinmetz MO. Proc. Natl. Acad. Sci. U.S.A. 102 13891-13896 (2005)
  4. Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: the Pax6 example. Alibés A, Nadra AD, De Masi F, Bulyk ML, Serrano L, Stricher F. Nucleic Acids Res. 38 7422-7431 (2010)
  5. The structural pathway of interleukin 1 (IL-1) initiated signaling reveals mechanisms of oncogenic mutations and SNPs in inflammation and cancer. Acuner Ozbabacan SE, Gursoy A, Nussinov R, Keskin O. PLoS Comput. Biol. 10 e1003470 (2014)
  6. Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding. He X, Chatterjee R, John S, Bravo H, Sathyanarayana BK, Biddie SC, FitzGerald PC, Stamatoyannopoulos JA, Hager GL, Vinson C. BMC Genomics 14 428 (2013)
  7. Small molecule inhibitors targeting activator protein 1 (AP-1). Ye N, Ding Y, Wild C, Shen Q, Zhou J. J. Med. Chem. 57 6930-6948 (2014)
  8. Blue light-induced LOV domain dimerization enhances the affinity of Aureochrome 1a for its target DNA sequence. Heintz U, Schlichting I. Elife 5 e11860 (2016)
  9. Quantitative modeling of dose-response and drug combination based on pathway network. Gu J, Zhang X, Ma Y, Li N, Luo F, Cao L, Wang Z, Yuan G, Chen L, Xiao W, Xu X. J Cheminform 7 19 (2015)
  10. DNA-binding residues and binding mode prediction with binding-mechanism concerned models. Huang YF, Huang CC, Liu YC, Oyang YJ, Huang CK. BMC Genomics 10 Suppl 3 S23 (2009)
  11. Free energy of binding of coiled-coil complexes with different electrostatic environments: the influence of force field polarisation and capping. Zuo ZL, Guo L, Mancera RL. Nat Prod Bioprospect 4 285-295 (2014)
  12. Anti-cancer effect of snake venom toxin through down regulation of AP-1 mediated PRDX6 expression. Lee HL, Park MH, Son DJ, Song HS, Kim JH, Ko SC, Song MJ, Lee WH, Yoon JH, Ham YW, Han SB, Hong JT. Oncotarget 6 22139-22151 (2015)
  13. In-vitro analysis of selective nutraceuticals binding to human transcription factors through computer aided molecular docking predictions. Teimouri M, Junaid M, Saleem S, Khan A, Ali A. Bioinformation 12 354-358 (2016)


Reviews citing this publication (46)

  1. Branched-chain amino acids differently modulate catabolic and anabolic states in mammals: a pharmacological point of view. Bifari F, Nisoli E. Br. J. Pharmacol. 174 1366-1377 (2017)
  2. The accommodation index measures the perturbation associated with insertions and deletions in coiled-coils: Application to understand signaling in histidine kinases. Schmidt NW, Grigoryan G, DeGrado WF. Protein Sci. 26 414-435 (2017)
  3. Designing helical peptide inhibitors of protein-protein interactions. Rezaei Araghi R, Keating AE. Curr. Opin. Struct. Biol. 39 27-38 (2016)
  4. Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation. Melnik BC. Int J Mol Sci 16 17048-17087 (2015)
  5. Bimolecular Fluorescence Complementation (BiFC) Analysis: Advances and Recent Applications for Genome-Wide Interaction Studies. Miller KE, Kim Y, Huh WK, Park HO. J. Mol. Biol. 427 2039-2055 (2015)
  6. bZIPs and WRKYs: two large transcription factor families executing two different functional strategies. Llorca CM, Potschin M, Zentgraf U. Front Plant Sci 5 169 (2014)
  7. Designing specific protein-protein interactions using computation, experimental library screening, or integrated methods. Chen TS, Keating AE. Protein Sci. 21 949-963 (2012)
  8. Nuclear import by karyopherin-βs: recognition and inhibition. Chook YM, Süel KE. Biochim. Biophys. Acta 1813 1593-1606 (2011)
  9. Combinatorial control of ATF4-dependent gene transcription in osteoblasts. St-Arnaud R, Hekmatnejad B. Ann. N. Y. Acad. Sci. 1237 11-18 (2011)
  10. The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation. Tsukada J, Yoshida Y, Kominato Y, Auron PE. Cytokine 54 6-19 (2011)
  11. Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes. Uversky VN. Chem Soc Rev 40 1623-1634 (2011)
  12. Coiled coils: attractive protein folding motifs for the fabrication of self-assembled, responsive and bioactive materials. Apostolovic B, Danial M, Klok HA. Chem Soc Rev 39 3541-3575 (2010)
  13. Self-assembly of coiled coils in synthetic biology: inspiration and progress. Robson Marsden H, Kros A. Angew. Chem. Int. Ed. Engl. 49 2988-3005 (2010)
  14. The Yap family and its role in stress response. Rodrigues-Pousada C, Menezes RA, Pimentel C. Yeast 27 245-258 (2010)
  15. Biological actions of curcumin on articular chondrocytes. Henrotin Y, Clutterbuck AL, Allaway D, Lodwig EM, Harris P, Mathy-Hartert M, Shakibaei M, Mobasheri A. Osteoarthr. Cartil. 18 141-149 (2010)
  16. The importance of being flexible: the case of basic region leucine zipper transcriptional regulators. Miller M. Curr. Protein Pept. Sci. 10 244-269 (2009)
  17. Composition-driven surface domain structuring mediated by sphingolipids and membrane-active proteins. Above the nano- but under the micro-scale: mesoscopic biochemical/structural cross-talk in biomembranes. Maggio B, Borioli GA, Del Boca M, De Tullio L, Fanani ML, Oliveira RG, Rosetti CM, Wilke N. Cell Biochem. Biophys. 50 79-109 (2008)
  18. Peptide, peptidomimetic and small-molecule drug discovery targeting HIV-1 host-cell attachment and entry through gp120, gp41, CCR5 and CXCR4. Kazmierski WM, Kenakin TP, Gudmundsson KS. Chem Biol Drug Des 67 13-26 (2006)
  19. Coiled coil domains: stability, specificity, and biological implications. Mason JM, Arndt KM. Chembiochem 5 170-176 (2004)
  20. Yeast activator proteins and stress response: an overview. Rodrigues-Pousada CA, Nevitt T, Menezes R, Azevedo D, Pereira J, Amaral C. FEBS Lett. 567 80-85 (2004)
  21. A tale of early response genes. Sng JC, Taniura H, Yoneda Y. Biol. Pharm. Bull. 27 606-612 (2004)
  22. Transcription factor activation in response to cutaneous injury: role of AP-1 in reepithelialization. Yates S, Rayner TE. Wound Repair Regen 10 5-15 (2002)
  23. Classification of human B-ZIP proteins based on dimerization properties. Vinson C, Myakishev M, Acharya A, Mir AA, Moll JR, Bonovich M. Mol. Cell. Biol. 22 6321-6335 (2002)
  24. Fortuitous convergences: the beginnings of JUN. Vogt PK. Nat. Rev. Cancer 2 465-469 (2002)
  25. Gel-based fluorescence resonance energy transfer (gelFRET) analysis of nucleoprotein complex architecture. Ramirez-Carrozzi V, Kerppola T. Methods 25 31-43 (2001)
  26. Regulated assembly of transcription factors and control of transcription initiation. Beckett D. J. Mol. Biol. 314 335-352 (2001)
  27. Plant bZIP G-box binding factors. Modular structure and activation mechanisms. Sibéril Y, Doireau P, Gantet P. Eur. J. Biochem. 268 5655-5666 (2001)
  28. The advantages of ambiguous orientation. Erlanson DA. Chem. Biol. 7 R81-4 (2000)
  29. What are oligomerization domains good for? Engel J, Kammerer RA. Matrix Biol. 19 283-288 (2000)
  30. Electrostatic mechanisms of DNA deformation. Williams LD, Maher LJ. Annu Rev Biophys Biomol Struct 29 497-521 (2000)
  31. Combinatorial gene regulation by eukaryotic transcription factors. Chen L. Curr. Opin. Struct. Biol. 9 48-55 (1999)
  32. Multiprotein-DNA complexes in transcriptional regulation. Wolberger C. Annu Rev Biophys Biomol Struct 28 29-56 (1999)
  33. Conformational homogeneity in molecular recognition by proteolytic enzymes. Tyndall JD, Fairlie DP. J. Mol. Recognit. 12 363-370 (1999)
  34. DNA bending and the curious case of Fos/Jun. McGill G, Fisher DE. Chem. Biol. 5 R29-38 (1998)
  35. Combinatorial transcription factors. Wolberger C. Curr. Opin. Genet. Dev. 8 552-559 (1998)
  36. Transcription: activation by cooperating conformations. Travers A. Curr. Biol. 8 R616-8 (1998)
  37. Transcriptional cooperativity: bending over backwards and doing the flip. Kerppola TK. Structure 6 549-554 (1998)
  38. Dimerization as a regulatory mechanism in signal transduction. Klemm JD, Schreiber SL, Crabtree GR. Annu. Rev. Immunol. 16 569-592 (1998)
  39. Study of gene regulation by NF-kappa B and AP-1 in response to reactive oxygen intermediates. Müller JM, Rupec RA, Baeuerle PA. Methods 11 301-312 (1997)
  40. The Maf transcription factors: regulators of differentiation. Blank V, Andrews NC. Trends Biochem. Sci. 22 437-441 (1997)
  41. Egr transcription factors in the nervous system. Beckmann AM, Wilce PA. Neurochem. Int. 31 477-510 (1997)
  42. Eukaryotic transcription factor-DNA complexes. Patikoglou G, Burley SK. Annu Rev Biophys Biomol Struct 26 289-325 (1997)
  43. Transcription factor AP-1, and the role of Fra-2. Foletta VC. Immunol. Cell Biol. 74 121-133 (1996)
  44. Boehringer Mannheim award lecture 1995. La conference Boehringer Mannheim 1995. De novo design of alpha-helical proteins: basic research to medical applications. Hodges RS. Biochem. Cell Biol. 74 133-154 (1996)
  45. Do basic region-leucine zipper proteins bend their DNA targets ... does it matter? Hagerman PJ. Proc. Natl. Acad. Sci. U.S.A. 93 9993-9996 (1996)
  46. Unraveling transposition: gamma delta resolvase in complex with DNA. Mondragón A. Structure 3 755-758 (1995)

Articles citing this publication (259)

  1. Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Hu CD, Chinenov Y, Kerppola TK. Mol. Cell 9 789-798 (2002)
  2. Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation. Khokhlatchev AV, Canagarajah B, Wilsbacher J, Robinson M, Atkinson M, Goldsmith E, Cobb MH. Cell 93 605-615 (1998)
  3. Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling. Shi Y, Wang YF, Jayaraman L, Yang H, Massagué J, Pavletich NP. Cell 94 585-594 (1998)
  4. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Fernandes L, Rodrigues-Pousada C, Struhl K. Mol. Cell. Biol. 17 6982-6993 (1997)
  5. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Tahirov TH, Inoue-Bungo T, Morii H, Fujikawa A, Sasaki M, Kimura K, Shiina M, Sato K, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Cell 104 755-767 (2001)
  6. Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun. Macián F, García-Rodríguez C, Rao A. EMBO J. 19 4783-4795 (2000)
  7. Geometric analysis and comparison of protein-DNA interfaces: why is there no simple code for recognition? Pabo CO, Nekludova L. J. Mol. Biol. 301 597-624 (2000)
  8. Multiallelic recognition: nonself-dependent dimerization of the bE and bW homeodomain proteins in Ustilago maydis. Kämper J, Reichmann M, Romeis T, Bölker M, Kahmann R. Cell 81 73-83 (1995)
  9. Predicting oligomerization states of coiled coils. Woolfson DN, Alber T. Protein Sci. 4 1596-1607 (1995)
  10. Cortexillins, major determinants of cell shape and size, are actin-bundling proteins with a parallel coiled-coil tail. Faix J, Steinmetz M, Boves H, Kammerer RA, Lottspeich F, Mintert U, Murphy J, Stock A, Aebi U, Gerisch G. Cell 86 631-642 (1996)
  11. Promoter specificity and biological activity of tethered AP-1 dimers. Bakiri L, Matsuo K, Wisniewska M, Wagner EF, Yaniv M. Mol. Cell. Biol. 22 4952-4964 (2002)
  12. The structure of docking domains in modular polyketide synthases. Broadhurst RW, Nietlispach D, Wheatcroft MP, Leadlay PF, Weissman KJ. Chem. Biol. 10 723-731 (2003)
  13. Buried polar residues and structural specificity in the GCN4 leucine zipper. Gonzalez L, Woolfson DN, Alber T. Nat. Struct. Biol. 3 1011-1018 (1996)
  14. The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage. Rep M, Proft M, Remize F, Tamás M, Serrano R, Thevelein JM, Hohmann S. Mol. Microbiol. 40 1067-1083 (2001)
  15. The K domain mediates heterodimerization of the Arabidopsis floral organ identity proteins, APETALA3 and PISTILLATA. Yang Y, Fanning L, Jack T. Plant J. 33 47-59 (2003)
  16. Kaposi's sarcoma-associated herpesvirus encodes a bZIP protein with homology to BZLF1 of Epstein-Barr virus. Lin SF, Robinson DR, Miller G, Kung HJ. J. Virol. 73 1909-1917 (1999)
  17. The role of position a in determining the stability and oligomerization state of alpha-helical coiled coils: 20 amino acid stability coefficients in the hydrophobic core of proteins. Wagschal K, Tripet B, Lavigne P, Mant C, Hodges RS. Protein Sci. 8 2312-2329 (1999)
  18. Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation. Zhang X, Wrzeszczynska MH, Horvath CM, Darnell JE. Mol. Cell. Biol. 19 7138-7146 (1999)
  19. Dependence of globin gene expression in mouse erythroleukemia cells on the NF-E2 heterodimer. Kotkow KJ, Orkin SH. Mol. Cell. Biol. 15 4640-4647 (1995)
  20. Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. Panne D, Maniatis T, Harrison SC. EMBO J. 23 4384-4393 (2004)
  21. A direct physical association between ETS and AP-1 transcription factors in normal human T cells. Bassuk AG, Leiden JM. Immunity 3 223-237 (1995)
  22. The interferon-inducible p202 protein as a modulator of transcription: inhibition of NF-kappa B, c-Fos, and c-Jun activities. Min W, Ghosh S, Lengyel P. Mol. Cell. Biol. 16 359-368 (1996)
  23. Helix bending as a factor in protein/DNA recognition. Dickerson RE, Chiu TK. Biopolymers 44 361-403 (1997)
  24. A role for CH...O interactions in protein-DNA recognition. Mandel-Gutfreund Y, Margalit H, Jernigan RL, Zhurkin VB. J. Mol. Biol. 277 1129-1140 (1998)
  25. Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers. Zhu L, Wilken J, Phillips NB, Narendra U, Chan G, Stratton SM, Kent SB, Weiss MA. Genes Dev. 14 1750-1764 (2000)
  26. A periodic table of coiled-coil protein structures. Moutevelis E, Woolfson DN. J. Mol. Biol. 385 726-732 (2009)
  27. Mating type in Chlamydomonas is specified by mid, the minus-dominance gene. Ferris PJ, Goodenough UW. Genetics 146 859-869 (1997)
  28. A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone beta gene by gonadotropin-releasing hormone. Coss D, Jacobs SB, Bender CE, Mellon PL. J. Biol. Chem. 279 152-162 (2004)
  29. Salt effects on protein stability: two-stranded alpha-helical coiled-coils containing inter- or intrahelical ion pairs. Kohn WD, Kay CM, Hodges RS. J. Mol. Biol. 267 1039-1052 (1997)
  30. Inter-helical interactions in the leucine zipper coiled coil dimer: pH and salt dependence of coupling energy between charged amino acids. Krylov D, Barchi J, Vinson C. J. Mol. Biol. 279 959-972 (1998)
  31. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Tsai YC, Greco TM, Boonmee A, Miteva Y, Cristea IM. Mol. Cell Proteomics 11 60-76 (2012)
  32. The crystal structure of the designed trimeric coiled coil coil-VaLd: implications for engineering crystals and supramolecular assemblies. Ogihara NL, Weiss MS, Degrado WF, Eisenberg D. Protein Sci. 6 80-88 (1997)
  33. High resolution genome wide binding event finding and motif discovery reveals transcription factor spatial binding constraints. Guo Y, Mahony S, Gifford DK. PLoS Comput. Biol. 8 e1002638 (2012)
  34. Structural model for the cooperative assembly of HIV-1 Rev multimers on the RRE as deduced from analysis of assembly-defective mutants. Jain C, Belasco JG. Mol. Cell 7 603-614 (2001)
  35. Predicting specificity in bZIP coiled-coil protein interactions. Fong JH, Keating AE, Singh M. Genome Biol. 5 R11 (2004)
  36. Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper. Lavigne P, Crump MP, Gagné SM, Hodges RS, Kay CM, Sykes BD. J. Mol. Biol. 281 165-181 (1998)
  37. BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. Bhende PM, Seaman WT, Delecluse HJ, Kenney SC. J. Virol. 79 7338-7348 (2005)
  38. Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1. Aikawa Y, Morimoto K, Yamamoto T, Chaki H, Hashiramoto A, Narita H, Hirono S, Shiozawa S. Nat. Biotechnol. 26 817-823 (2008)
  39. The coiled-coil trigger site of the rod domain of cortexillin I unveils a distinct network of interhelical and intrahelical salt bridges. Burkhard P, Kammerer RA, Steinmetz MO, Bourenkov GP, Aebi U. Structure 8 223-230 (2000)
  40. Buried asparagines determine the dimerization specificities of leucine zipper mutants. Zeng X, Herndon AM, Hu JC. Proc. Natl. Acad. Sci. U.S.A. 94 3673-3678 (1997)
  41. Mechanism for specificity by HMG-1 in enhanceosome assembly. Ellwood KB, Yen YM, Johnson RC, Carey M. Mol. Cell. Biol. 20 4359-4370 (2000)
  42. Alteration of a single serine in the basic domain of the Epstein-Barr virus ZEBRA protein separates its functions of transcriptional activation and disruption of latency. Francis AL, Gradoville L, Miller G. J. Virol. 71 3054-3061 (1997)
  43. Extending dimerization interfaces: the bZIP basic region can form a coiled coil. Krylov D, Olive M, Vinson C. EMBO J. 14 5329-5337 (1995)
  44. A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo. Cronican JJ, Beier KT, Davis TN, Tseng JC, Li W, Thompson DB, Shih AF, May EM, Cepko CL, Kung AL, Zhou Q, Liu DR. Chem. Biol. 18 833-838 (2011)
  45. Structural basis of lytic cycle activation by the Epstein-Barr virus ZEBRA protein. Petosa C, Morand P, Baudin F, Moulin M, Artero JB, Müller CW. Mol. Cell 21 565-572 (2006)
  46. A bZIP transcription factor from Phytophthora interacts with a protein kinase and is required for zoospore motility and plant infection. Blanco FA, Judelson HS. Mol. Microbiol. 56 638-648 (2005)
  47. Orientation, positional, additivity, and oligomerization-state effects of interhelical ion pairs in alpha-helical coiled-coils. Kohn WD, Kay CM, Hodges RS. J. Mol. Biol. 283 993-1012 (1998)
  48. CpG-methylation regulates a class of Epstein-Barr virus promoters. Bergbauer M, Kalla M, Schmeinck A, Göbel C, Rothbauer U, Eck S, Benet-Pagès A, Strom TM, Hammerschmidt W. PLoS Pathog. 6 e1001114 (2010)
  49. The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site. Li Y, Mui S, Brown JH, Strand J, Reshetnikova L, Tobacman LS, Cohen C. Proc. Natl. Acad. Sci. U.S.A. 99 7378-7383 (2002)
  50. Comparing transcriptional activation and autostimulation by ZEBRA and ZEBRA/c-Fos chimeras. Kolman JL, Taylor N, Gradoville L, Countryman J, Miller G. J. Virol. 70 1493-1504 (1996)
  51. B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partners. Fassler J, Landsman D, Acharya A, Moll JR, Bonovich M, Vinson C. Genome Res. 12 1190-1200 (2002)
  52. Structural basis of DNA bending and oriented heterodimer binding by the basic leucine zipper domains of Fos and Jun. Leonard DA, Rajaram N, Kerppola TK. Proc. Natl. Acad. Sci. U.S.A. 94 4913-4918 (1997)
  53. Fos and Jun do not bend the AP-1 recognition site. Sitlani A, Crothers DM. Proc. Natl. Acad. Sci. U.S.A. 93 3248-3252 (1996)
  54. Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis. Yuan Z, Gong S, Luo J, Zheng Z, Song B, Ma S, Guo J, Hu C, Thiel G, Vinson C, Hu CD, Wang Y, Li M. Mol. Cell. Biol. 29 2431-2442 (2009)
  55. Measurement of the DNA bend angle induced by the catabolite activator protein using Monte Carlo simulation of cyclization kinetics. Kahn JD, Crothers DM. J. Mol. Biol. 276 287-309 (1998)
  56. Activation of the Epstein-Barr virus transcription factor BZLF1 by 12-O-tetradecanoylphorbol-13-acetate-induced phosphorylation. Baumann M, Mischak H, Dammeier S, Kolch W, Gires O, Pich D, Zeidler R, Delecluse HJ, Hammerschmidt W. J. Virol. 72 8105-8114 (1998)
  57. The binding of a Fos/Jun heterodimer can completely disrupt the structure of a nucleosome. Ng KW, Ridgway P, Cohen DR, Tremethick DJ. EMBO J. 16 2072-2085 (1997)
  58. Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma. DaFonseca CJ, Shu F, Zhang JJ. Proc. Natl. Acad. Sci. U.S.A. 98 3034-3039 (2001)
  59. Structures of three distinct activator-TFIID complexes. Liu WL, Coleman RA, Ma E, Grob P, Yang JL, Zhang Y, Dailey G, Nogales E, Tjian R. Genes Dev. 23 1510-1521 (2009)
  60. Amino acid substitutions reveal distinct functions of serine 186 of the ZEBRA protein in activation of early lytic cycle genes and synergy with the Epstein-Barr virus R transactivator. Francis A, Ragoczy T, Gradoville L, Heston L, El-Guindy A, Endo Y, Miller G. J. Virol. 73 4543-4551 (1999)
  61. Oligomerization properties of GCN4 leucine zipper e and g position mutants. Zeng X, Zhu H, Lashuel HA, Hu JC. Protein Sci. 6 2218-2226 (1997)
  62. A specific lysine in c-Jun is required for transcriptional repression by E1A and is acetylated by p300. Vries RG, Prudenziati M, Zwartjes C, Verlaan M, Kalkhoven E, Zantema A. EMBO J. 20 6095-6103 (2001)
  63. The bZIP-type transcription factor FlbB regulates distinct morphogenetic stages of colony formation in Aspergillus nidulans. Etxebeste O, Herrero-García E, Araújo-Bazán L, Rodríguez-Urra AB, Garzia A, Ugalde U, Espeso EA. Mol. Microbiol. 73 775-789 (2009)
  64. Structure-based prediction of bZIP partnering specificity. Grigoryan G, Keating AE. J. Mol. Biol. 355 1125-1142 (2006)
  65. Fos and Jun bend the AP-1 site: effects of probe geometry on the detection of protein-induced DNA bending. Kerppola TK. Proc. Natl. Acad. Sci. U.S.A. 93 10117-10122 (1996)
  66. Cryo-electron microscopy structure of an adenovirus-integrin complex indicates conformational changes in both penton base and integrin. Lindert S, Silvestry M, Mullen TM, Nemerow GR, Stewart PL. J. Virol. 83 11491-11501 (2009)
  67. DNA-binding domains of Fos and Jun do not induce DNA curvature: an investigation with solution and gel methods. Sitlani A, Crothers DM. Proc. Natl. Acad. Sci. U.S.A. 95 1404-1409 (1998)
  68. Production of soluble alphabeta T-cell receptor heterodimers suitable for biophysical analysis of ligand binding. Willcox BE, Gao GF, Wyer JR, O'Callaghan CA, Boulter JM, Jones EY, van der Merwe PA, Bell JI, Jakobsen BK. Protein Sci. 8 2418-2423 (1999)
  69. c-Jun homodimers can function as a context-specific coactivator. Grondin B, Lefrancois M, Tremblay M, Saint-Denis M, Haman A, Waga K, Bédard A, Tenen DG, Hoang T. Mol. Cell. Biol. 27 2919-2933 (2007)
  70. Molecular cloning and characterization of mouse EBAG9, homolog of a human cancer associated surface antigen: expression and regulation by estrogen. Tsuchiya F, Ikeda K, Tsutsumi O, Hiroi H, Momoeda M, Taketani Y, Muramatsu M, Inoue S. Biochem. Biophys. Res. Commun. 284 2-10 (2001)
  71. Role of c-myc regulation in Zta-mediated induction of the cyclin-dependent kinase inhibitors p21 and p27 and cell growth arrest. Rodriguez A, Jung EJ, Yin Q, Cayrol C, Flemington EK. Virology 284 159-169 (2001)
  72. Research Support, U.S. Gov't, P.H.S. Certain bZIP peptides bind DNA sequentially as monomers and dimerize on the DNA. Metallo SJ, Schepartz A. Nat. Struct. Biol. 4 115-117 (1997)
  73. Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization. Lamber EP, Vanhille L, Textor LC, Kachalova GS, Sieweke MH, Wilmanns M. EMBO J. 27 2006-2017 (2008)
  74. Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells. Stuhlmann-Laeisz C, Lang S, Chalaris A, Krzysztof P, Enge S, Eichler J, Klingmüller U, Samuel M, Ernst M, Rose-John S, Scheller J. Mol. Biol. Cell 17 2986-2995 (2006)
  75. Crystallographic snapshots along a protein-induced DNA-bending pathway. Horton NC, Perona JJ. Proc. Natl. Acad. Sci. U.S.A. 97 5729-5734 (2000)
  76. DNA bending by Fos-Jun and the orientation of heterodimer binding depend on the sequence of the AP-1 site. Rajaram N, Kerppola TK. EMBO J. 16 2917-2925 (1997)
  77. Structural basis of alternative DNA recognition by Maf transcription factors. Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T. Mol. Cell. Biol. 29 6232-6244 (2009)
  78. Evaluation of the energetic contribution of interhelical Coulombic interactions for coiled coil helix orientation specificity. McClain DL, Binfet JP, Oakley MG. J. Mol. Biol. 313 371-383 (2001)
  79. Molecular basis of cooperative DNA bending and oriented heterodimer binding in the NFAT1-Fos-Jun-ARRE2 complex. Diebold RJ, Rajaram N, Leonard DA, Kerppola TK. Proc. Natl. Acad. Sci. U.S.A. 95 7915-7920 (1998)
  80. Differential gene regulation by selective association of transcriptional coactivators and bZIP DNA-binding domains. Miotto B, Struhl K. Mol. Cell. Biol. 26 5969-5982 (2006)
  81. Lactate-sensitive response elements in genes involved in hyaluronan catabolism. Formby B, Stern R. Biochem. Biophys. Res. Commun. 305 203-208 (2003)
  82. Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor. Day CL, Alber T. J. Mol. Biol. 301 147-156 (2000)
  83. Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo. Huguier S, Baguet J, Perez S, van Dam H, Castellazzi M. Mol. Cell. Biol. 18 7020-7029 (1998)
  84. Assemblies of replication initiator protein on symmetric and asymmetric DNA sequences depend on multiple protein oligomerization surfaces. Urh M, Wu J, Wu J, Forest K, Inman RB, Filutowicz M. J. Mol. Biol. 283 619-631 (1998)
  85. A leucine zipper motif determines different functions in a DNA replication protein. Garcia de Viedma D, Giraldo R, Rivas G, Fernández-Tresguerres E, Diaz-Orejas R. EMBO J. 15 925-934 (1996)
  86. Stepwise transformation of rat embryo fibroblasts: c-Jun, JunB, or JunD can cooperate with Ras for focus formation, but a c-Jun-containing heterodimer is required for immortalization. Vandel L, Montreau N, Vial E, Pfarr CM, Binetruy B, Castellazzi M. Mol. Cell. Biol. 16 1881-1888 (1996)
  87. Importance of accurate DNA structures in solution: the Jun-Fos model. Heddi B, Foloppe N, Oguey C, Hartmann B. J. Mol. Biol. 382 956-970 (2008)
  88. The role of cerebellar genes in pathology of autism and schizophrenia. Fatemi SH, Reutiman TJ, Folsom TD, Sidwell RW. Cerebellum 7 279-294 (2008)
  89. Amino acid residues required for physical and cooperative transcriptional interaction of STAT3 and AP-1 proteins c-Jun and c-Fos. Ginsberg M, Czeko E, Müller P, Ren Z, Chen X, Darnell JE. Mol. Cell. Biol. 27 6300-6308 (2007)
  90. A leucine-rich motif targets Pseudomonas aeruginosa ExoS within mammalian cells. Zhang Y, Barbieri JT. Infect. Immun. 73 7938-7945 (2005)
  91. DNA sequence-dependent folding determines the divergence in binding specificities between Maf and other bZIP proteins. Dlakić M, Grinberg AV, Leonard DA, Kerppola TK. EMBO J. 20 828-840 (2001)
  92. Electrostatic interactions in leucine zippers: thermodynamic analysis of the contributions of Glu and His residues and the effect of mutating salt bridges. Marti DN, Bosshard HR. J. Mol. Biol. 330 621-637 (2003)
  93. The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency. Chytil M, Peterson BR, Erlanson DA, Verdine GL. Proc. Natl. Acad. Sci. U.S.A. 95 14076-14081 (1998)
  94. Rat maf-related factors: the specificities of DNA binding and heterodimer formation. Matsushima-Hibiya Y, Nishi S, Sakai M. Biochem. Biophys. Res. Commun. 245 412-418 (1998)
  95. The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children. Almén MS, Jacobsson JA, Shaik JH, Olszewski PK, Cedernaes J, Alsiö J, Sreedharan S, Levine AS, Fredriksson R, Marcus C, Schiöth HB. BMC Med. Genet. 11 58 (2010)
  96. Conformation of the c-Fos/c-Jun complex in vivo: a combined FRET, FCCS, and MD-modeling study. Vámosi G, Baudendistel N, von der Lieth CW, Szalóki N, Mocsár G, Müller G, Brázda P, Waldeck W, Damjanovich S, Langowski J, Tóth K. Biophys. J. 94 2859-2868 (2008)
  97. Electrostatic contributions to the stability of the GCN4 leucine zipper structure. Matousek WM, Ciani B, Fitch CA, Garcia-Moreno B, Kammerer RA, Alexandrescu AT. J. Mol. Biol. 374 206-219 (2007)
  98. NMR solution structure of a highly stable de novo heterodimeric coiled-coil. Lindhout DA, Litowski JR, Mercier P, Hodges RS, Sykes BD. Biopolymers 75 367-375 (2004)
  99. Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1. Ibarra-Molero B, Zitzewitz JA, Matthews CR. J. Mol. Biol. 336 989-996 (2004)
  100. TNF-alpha mediates pseudorabies virus-induced apoptosis via the activation of p38 MAPK and JNK/SAPK signaling. Yeh CJ, Lin PY, Liao MH, Liu HJ, Lee JW, Chiu SJ, Hsu HY, Shih WL. Virology 381 55-66 (2008)
  101. Dynamics of Fos-Jun-NFAT1 complexes. Ramirez-Carrozzi VR, Kerppola TK. Proc. Natl. Acad. Sci. U.S.A. 98 4893-4898 (2001)
  102. DNA bending determines Fos-Jun heterodimer orientation. Leonard DA, Kerppola TK. Nat. Struct. Biol. 5 877-881 (1998)
  103. SKN-1 domain folding and basic region monomer stabilization upon DNA binding. Carroll AS, Gilbert DE, Liu X, Cheung JW, Michnowicz JE, Wagner G, Ellenberger TE, Blackwell TK. Genes Dev. 11 2227-2238 (1997)
  104. A modified version of a Fos-associated cluster in HBZ affects Jun transcriptional potency. Hivin P, Arpin-André C, Clerc I, Barbeau B, Mesnard JM. Nucleic Acids Res. 34 2761-2772 (2006)
  105. Sequence-specific recognition of DNA by hydrophobic, alanine-rich mutants of the basic region/leucine zipper motif investigated by fluorescence anisotropy. Bird GH, Lajmi AR, Shin JA. Biopolymers 65 10-20 (2002)
  106. Human KRML (MAFB): cDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. Wang PW, Eisenbart JD, Cordes SP, Barsh GS, Stoffel M, Le Beau MM. Genomics 59 275-281 (1999)
  107. DNA binding of Jun and Fos bZip domains: homodimers and heterodimers induce a DNA conformational change in solution. John M, Leppik R, Busch SJ, Granger-Schnarr M, Schnarr M. Nucleic Acids Res. 24 4487-4494 (1996)
  108. Asymmetric recognition of nonconsensus AP-1 sites by Fos-Jun and Jun-Jun influences transcriptional cooperativity with NFAT1. Ramirez-Carrozzi V, Kerppola T. Mol. Cell. Biol. 23 1737-1749 (2003)
  109. Disruption of Epstein-Barr virus latency in the absence of phosphorylation of ZEBRA by protein kinase C. El-Guindy AS, Heston L, Endo Y, Cho MS, Miller G. J. Virol. 76 11199-11208 (2002)
  110. Magnesium is required for specific DNA binding of the CREB B-ZIP domain. Moll JR, Acharya A, Gal J, Mir AA, Vinson C. Nucleic Acids Res. 30 1240-1246 (2002)
  111. Selecting protein targets for structural genomics of Pyrobaculum aerophilum: validating automated fold assignment methods by using binary hypothesis testing. Mallick P, Goodwill KE, Fitz-Gibbon S, Miller JH, Eisenberg D. Proc. Natl. Acad. Sci. U.S.A. 97 2450-2455 (2000)
  112. The DNA structure responds differently to physiological concentrations of K(+) or Na(+). Heddi B, Foloppe N, Hantz E, Hartmann B. J. Mol. Biol. 368 1403-1411 (2007)
  113. Two forms of replication initiator protein: positive and negative controls. Wu J, Sektas M, Chen D, Filutowicz M. Proc. Natl. Acad. Sci. U.S.A. 94 13967-13972 (1997)
  114. Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors. Sun D, Junger WG, Yuan C, Zhang W, Bao Y, Qin D, Wang C, Tan L, Qi B, Zhu D, Zhang X, Yu T. Stem Cells 31 1170-1180 (2013)
  115. Coupling of folding and DNA-binding in the bZIP domains of Jun-Fos heterodimeric transcription factor. Seldeen KL, McDonald CB, Deegan BJ, Farooq A. Arch. Biochem. Biophys. 473 48-60 (2008)
  116. Long-range electrostatic interactions influence the orientation of Fos-Jun binding at AP-1 sites. Ramirez-Carrozzi VR, Kerppola TK. J. Mol. Biol. 305 411-427 (2001)
  117. Selectional and mutational scope of peptides sequestering the Jun-Fos coiled-coil domain. Hagemann UB, Mason JM, Müller KM, Arndt KM. J. Mol. Biol. 381 73-88 (2008)
  118. Inhibition of AP-1 transcription activator induces myc-dependent apoptosis in HL60 cells. Park S, Hahm ER, Lee DK, Yang CH. J. Cell. Biochem. 91 973-986 (2004)
  119. Mapping of the laminin-binding site of the N-terminal agrin domain (NtA). Mascarenhas JB, Rüegg MA, Winzen U, Halfter W, Engel J, Stetefeld J. EMBO J. 22 529-536 (2003)
  120. Characterization of the dimerization domain in BglG, an RNA-binding transcriptional antiterminator from Escherichia coli. Boss A, Nussbaum-Shochat A, Amster-Choder O. J. Bacteriol. 181 1755-1766 (1999)
  121. Effects of phosphate neutralization on the shape of the AP-1 transcription factor binding site in duplex DNA. Tomky LA, Strauss-Soukup JK, Maher LJ. Nucleic Acids Res. 26 2298-2305 (1998)
  122. The oncogene c-Jun impedes somatic cell reprogramming. Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Guo L, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D. Nat. Cell Biol. 17 856-867 (2015)
  123. 2-hydroxycinnamaldehyde inhibits SW620 colon cancer cell growth through AP-1 inactivation. Lee CW, Lee SH, Lee JW, Ban JO, Lee SY, Yoo HS, Jung JK, Moon DC, Oh KW, Hong JT. J. Pharmacol. Sci. 104 19-28 (2007)
  124. Crystal structure of a coiled-coil domain from human ROCK I. Tu D, Li Y, Song HK, Toms AV, Gould CJ, Ficarro SB, Marto JA, Goode BL, Eck MJ. PLoS ONE 6 e18080 (2011)
  125. c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs. Gustems M, Woellmer A, Rothbauer U, Eck SH, Wieland T, Lutter D, Hammerschmidt W. Nucleic Acids Res. 42 3059-3072 (2014)
  126. Indications of associations of the porcine FOS proto-oncogene with skeletal muscle fibre traits. Reiner G, Heinricy L, Müller E, Geldermann H, Dzapo V. Anim. Genet. 33 49-55 (2002)
  127. The leucine zipper may induce electrophoretic mobility anomalies without DNA bending. McCormick RJ, Badalian T, Fisher DE. Proc. Natl. Acad. Sci. U.S.A. 93 14434-14439 (1996)
  128. Amino acids in the basic domain of Epstein-Barr virus ZEBRA protein play distinct roles in DNA binding, activation of early lytic gene expression, and promotion of viral DNA replication. Heston L, El-Guindy A, Countryman J, Dela Cruz C, Delecluse HJ, Miller G. J. Virol. 80 9115-9133 (2006)
  129. The role of a basic amino acid cluster in target site selection and non-specific binding of bZIP peptides to DNA. Metallo SJ, Paolella DN, Schepartz A. Nucleic Acids Res. 25 2967-2972 (1997)
  130. Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF. Martin ML, Lieberman PM, Curran T. Mol. Cell. Biol. 16 2110-2118 (1996)
  131. In vivo selection of basic region-leucine zipper proteins with altered DNA-binding specificities. Sera T, Schultz PG. Proc. Natl. Acad. Sci. U.S.A. 93 2920-2925 (1996)
  132. Photoreactions of aureochrome-1. Toyooka T, Hisatomi O, Takahashi F, Kataoka H, Terazima M. Biophys. J. 100 2801-2809 (2011)
  133. Phosphorylation within the MafA N terminus regulates C-terminal dimerization and DNA binding. Guo S, Vanderford NL, Stein R. J. Biol. Chem. 285 12655-12661 (2010)
  134. Mutations in the N-terminal coding region of the harpin protein Hpa1 from Xanthomonas oryzae cause loss of hypersensitive reaction induction in tobacco. Wang XY, Song CF, Miao WG, Ji ZL, Wang X, Zhang Y, Zhang JH, Hu JS, Borth W, Wang JS. Appl. Microbiol. Biotechnol. 81 359-369 (2008)
  135. Molecular cloning of a human MafF homologue, which specifically binds to the oxytocin receptor gene in term myometrium. Kimura T, Ivell R, Rust W, Mizumoto Y, Ogita K, Kusui C, Matsumura Y, Azuma C, Murata Y. Biochem. Biophys. Res. Commun. 264 86-92 (1999)
  136. Experimental identification of homodimerizing B-ZIP families in Homo sapiens. Acharya A, Rishi V, Moll J, Vinson C. J. Struct. Biol. 155 130-139 (2006)
  137. Adsorption of monovalent and multivalent cations and anions on DNA molecules. Allahyarov E, Löwen H, Gompper G. Phys Rev E Stat Nonlin Soft Matter Phys 68 061903 (2003)
  138. Detection of specific noncovalent interaction of peptide with DNA by MALDI-TOF. Luo SZ, Li YM, Qiang W, Zhao YF, Abe H, Nemoto T, Qin XR, Nakanishi H. J. Am. Soc. Mass Spectrom. 15 28-31 (2004)
  139. KapI, a non-essential member of the Pse1p/Imp5 karyopherin family, controls colonial and asexual development in Aspergillus nidulans. Etxebeste O, Markina-Iñarrairaegui A, Garzia A, Herrero-García E, Ugalde U, Espeso EA. Microbiology (Reading, Engl.) 155 3934-3945 (2009)
  140. High affinity binding of MEF-2C correlates with DNA bending. Meierhans D, Sieber M, Allemann RK. Nucleic Acids Res. 25 4537-4544 (1997)
  141. A comparison of the different DNA binding specificities of the bZip proteins C/EBP and GCN4. Koldin B, Suckow M, Seydel A, von Wilcken-Bergmann B, Müller-Hill B. Nucleic Acids Res. 23 4162-4169 (1995)
  142. bZIP transcription factors in the oomycete phytophthora infestans with novel DNA-binding domains are involved in defense against oxidative stress. Gamboa-Meléndez H, Huerta AI, Judelson HS. Eukaryotic Cell 12 1403-1412 (2013)
  143. The GCN4 bZIP targets noncognate gene regulatory sequences: quantitative investigation of binding at full and half sites. Chan IS, Fedorova AV, Shin JA. Biochemistry 46 1663-1671 (2007)
  144. Induction of cell growth by insulin and insulin-like growth factor-I is associated with Jun expression in the otic vesicle. León Y, Sanz C, Giráldez F, Varela-Nieto I. J. Comp. Neurol. 398 323-332 (1998)
  145. The activation specificities of wild-type and mutant Gcn4p in vivo can be different from the DNA binding specificities of the corresponding bZip peptides in vitro. Suckow M, Hollenberg CP. J. Mol. Biol. 276 887-902 (1998)
  146. DNA binding and transactivation properties of Fos variants with homodimerization capacity. Porte D, Oertel-Buchheit P, John M, Granger-Schnarr M, Schnarr M. Nucleic Acids Res. 25 3026-3033 (1997)
  147. Regulation of tissue factor gene expression in monocytes and endothelial cells: Thromboxane A2 as a new player. Bode M, Mackman N. Vascul. Pharmacol. 62 57-62 (2014)
  148. Truncated and helix-constrained peptides with high affinity and specificity for the cFos coiled-coil of AP-1. Rao T, Ruiz-Gómez G, Hill TA, Hoang HN, Fairlie DP, Mason JM. PLoS ONE 8 e59415 (2013)
  149. Single nucleotide variants of the TGACTCA motif modulate energetics and orientation of binding of the Jun-Fos heterodimeric transcription factor. Seldeen KL, McDonald CB, Deegan BJ, Farooq A. Biochemistry 48 1975-1983 (2009)
  150. ds-Oligonucleotide-peptide conjugates featuring peptides from the leucine-zipper region of Fos as switchable receptors for the oncoprotein Jun. Portela C, Albericio F, Eritja R, Castedo L, Mascareñas JL. Chembiochem 8 1110-1114 (2007)
  151. Fluctuations between stabilizing and destabilizing electrostatic contributions of ion pairs in conformers of the c-Myc-Max leucine zipper. Kumar S, Nussinov R. Proteins 41 485-497 (2000)
  152. The basic subdomain of the c-Jun oncoprotein. A joint CD, Fourier-transform infrared and NMR study. Krebs D, Dahmani B, el Antri S, Monnot M, Convert O, Mauffret O, Troalen F, Fermandjian S. Eur. J. Biochem. 231 370-380 (1995)
  153. Deciphering the combinatorial DNA-binding code of the CCAAT-binding complex and the iron-regulatory basic region leucine zipper (bZIP) transcription factor HapX. Hortschansky P, Ando E, Tuppatsch K, Arikawa H, Kobayashi T, Kato M, Haas H, Brakhage AA. J. Biol. Chem. 290 6058-6070 (2015)
  154. AP-1 binding transcriptionally regulates human neutral ceramidase. O'Neill SM, Houck KL, Yun JK, Fox TE, Kester M. Arch. Biochem. Biophys. 511 31-39 (2011)
  155. Design of peptide inhibitors that bind the bZIP domain of Epstein-Barr virus protein BZLF1. Chen TS, Reinke AW, Keating AE. J. Mol. Biol. 408 304-320 (2011)
  156. Efficient induction of nuclear aggresomes by specific single missense mutations in the DNA-binding domain of a viral AP-1 homolog. Park R, Wang'ondu R, Heston L, Shedd D, Miller G. J. Biol. Chem. 286 9748-9762 (2011)
  157. Identification of the bZIP and Rta homologues in the genome of rhesus monkey rhadinovirus. Lin SF, Robinson DR, Oh J, Jung JU, Luciw PA, Kung HJ. Virology 298 181-188 (2002)
  158. Repression of glucocorticoid receptor gene transcription by c-Jun. Cabral AL, Hays AN, Housley PR, Brentani MM, Martins VR. Mol. Cell. Endocrinol. 175 67-79 (2001)
  159. Enhancement of gene expression by transcription factor AP-1 is dependent on orientation of AP-1 element. Tu Z, Anders MW. Biochem. Biophys. Res. Commun. 238 285-288 (1997)
  160. Phosphorylation-induced Conformational Ensemble Switching in an Intrinsically Disordered Cancer/Testis Antigen. He Y, Chen Y, Mooney SM, Rajagopalan K, Bhargava A, Sacho E, Weninger K, Bryan PN, Kulkarni P, Orban J. J. Biol. Chem. 290 25090-25102 (2015)
  161. NFATc2 recruits cJun homodimers to an NFAT site to synergistically activate interleukin-2 transcription. Walters RD, Drullinger LF, Kugel JF, Goodrich JA. Mol. Immunol. 56 48-56 (2013)
  162. Latency of Epstein-Barr virus is disrupted by gain-of-function mutant cellular AP-1 proteins that preferentially bind methylated DNA. Yu KP, Heston L, Park R, Ding Z, Wang'ondu R, Delecluse HJ, Miller G. Proc. Natl. Acad. Sci. U.S.A. 110 8176-8181 (2013)
  163. Obesity risk gene TMEM18 encodes a sequence-specific DNA-binding protein. Jurvansuu JM, Goldman A. PLoS ONE 6 e25317 (2011)
  164. Characterization of the promoter region of TCblR/CD320 gene, the receptor for cellular uptake of transcobalamin-bound cobalamin. Jiang W, Sequeira JM, Nakayama Y, Lai SC, Quadros EV. Gene 466 49-55 (2010)
  165. Effects of disulfide bond formation and protein helicity on the aggregation of activating transcription factor 5. Ciaccio NA, Laurence JS. Mol. Pharm. 6 1205-1215 (2009)
  166. Thermodynamic analysis of the heterodimerization of leucine zippers of Jun and Fos transcription factors. Seldeen KL, McDonald CB, Deegan BJ, Farooq A. Biochem. Biophys. Res. Commun. 375 634-638 (2008)
  167. The GCN4 bZIP can bind to noncognate gene regulatory sequences. Fedorova AV, Chan IS, Shin JA. Biochim. Biophys. Acta 1764 1252-1259 (2006)
  168. Differential regulation of c-Fos and FosB in the rat brain after amygdala kindling. Madsen TM, Bolwig TG, Mikkelsen JD. Cell. Mol. Neurobiol. 26 87-100 (2006)
  169. A procedure for refining a coiled coil protein structure using x-ray fiber diffraction and modeling. Briki F, Doucet J, Etchebest C. Biophys. J. 83 1774-1783 (2002)
  170. The effect of DNA damage on the formation of protein/DNA complexes. Parsian AJ, Funk MC, Tao TY, Hunt CR. Mutat. Res. 501 105-113 (2002)
  171. Uncoiling c-Jun coiled coils: inhibitory effects of truncated Fos peptides on Jun dimerization and DNA binding in vitro. Yao S, Brickner M, Pares-Matos EI, Chmielewski J. Biopolymers 47 277-283 (1998)
  172. Protein-DNA interactions in the human beta-globin locus control region hypersensitive site-2 as revealed by four nitrogen mustards. Temple MD, Cairns MJ, Denny WA, Murray V. Nucleic Acids Res. 25 3255-3260 (1997)
  173. Small molecule screening identifies regulators of the transcription factor ΔFosB. Wang Y, Cesena TI, Ohnishi Y, Burger-Caplan R, Lam V, Kirchhoff PD, Larsen SD, Larsen MJ, Nestler EJ, Rudenko G. ACS Chem Neurosci 3 546-556 (2012)
  174. Monitoring protein-protein interactions in mammalian cells by trans-SUMOylation. Srivastav RK, Schwede S, Klaus M, Schwermann J, Gaestel M, Niedenthal R. Biochem. J. 438 495-503 (2011)
  175. Thermodynamic analysis of Jun-Fos coiled coil peptide antagonists. Worrall JA, Mason JM. FEBS J. 278 663-672 (2011)
  176. Negative cooperativity between juxtaposed E-box and cAMP/TPA responsive elements in the cholecystokinin gene promoter. Rourke IJ, Hansen TV, Nerlov C, Rehfeld JF, Nielsen FC. FEBS Lett. 448 15-18 (1999)
  177. Short, hydrophobic, alanine-based proteins based on the basic region/leucine zipper protein motif: overcoming inclusion body formation and protein aggregation during overexpression, purification, and renaturation. Lajmi AR, Wallace TR, Shin JA. Protein Expr. Purif. 18 394-403 (2000)
  178. Skn-1: evidence for a bipartite recognition helix in DNA binding. Pal S, Lo MC, Schmidt D, Pelczer I, Thurber S, Walker S. Proc. Natl. Acad. Sci. U.S.A. 94 5556-5561 (1997)
  179. Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice. Cho HY, Jedlicka AE, Gladwell W, Marzec J, McCaw ZR, Bienstock RJ, Kleeberger SR. Antioxid. Redox Signal. 22 325-338 (2015)
  180. Structural attributes for the recognition of weak and anomalous regions in coiled-coils of myosins and other motor proteins. Sunitha MS, Nair AG, Charya A, Jadhav K, Mukhopadhyay S, Sowdhamini R. BMC Res Notes 5 530 (2012)
  181. Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension. Sonawane PJ, Sahu BS, Sasi BK, Geedi P, Lenka G, Mahapatra NR. PLoS ONE 6 e16661 (2011)
  182. Evidence that the bZIP domains of the Jun transcription factor bind to DNA as monomers prior to folding and homodimerization. Seldeen KL, McDonald CB, Deegan BJ, Farooq A. Arch. Biochem. Biophys. 480 75-84 (2008)
  183. High-yield expression in E. coli and refolding of the bZIP domain of activating transcription factor 5. Ciaccio NA, Moreno ML, Bauer RL, Laurence JS. Protein Expr. Purif. 62 235-243 (2008)
  184. Hybrids of the bHLH and bZIP protein motifs display different DNA-binding activities in vivo vs. in vitro. Chow HK, Xu J, Shahravan SH, De Jong AT, Chen G, Shin JA. PLoS ONE 3 e3514 (2008)
  185. Tertiary structure prediction using mean-force potentials and internal energy functions: successful prediction for coiled-coil geometries. O'Donoghue SI, Nilges M. Fold Des 2 S47-52 (1997)
  186. Transcriptional regulation of the human chromogranin A gene by its 5' distal regulatory element: novel effects of orientation, structure, flanking sequences, and position on expression. Nolan EM, Cheung TC, Burton DW, Deftos LJ. Mol. Cell. Endocrinol. 124 51-62 (1996)
  187. Dissection of the basic subdomain of the c-Jun oncoprotein: a structural analysis of two peptide fragments by CD, Fourier-transform infrared and NMR. Krebs D, Dahmani B, Monnot M, Mauffret O, Troalen F, Fermandjian S. Eur. J. Biochem. 235 699-712 (1996)
  188. A DNA-bending protein interacts with an essential upstream regulatory element of the human embryonic beta-like globin gene. Dyer MA, Naidoo R, Hayes RJ, Larson CJ, Verdine GL, Baron MH. Mol. Cell. Biol. 16 829-838 (1996)
  189. miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis. Xu Z, Bu Y, Chitnis N, Koumenis C, Fuchs SY, Diehl JA. Nat Commun 7 11422 (2016)
  190. TNFAIP1 interacts with KCTD10 to promote the degradation of KCTD10 proteins and inhibit the transcriptional activities of NF-κB and AP-1. Hu X, Yan F, Wang F, Yang Z, Xiao L, Li L, Xiang S, Zhou J, Ding X, Zhang J. Mol. Biol. Rep. 39 9911-9919 (2012)
  191. α1-Acid glycoprotein induced effects in rat brain microvessel endothelial cells. Zhang S, Mark KS. Microvasc. Res. 84 161-168 (2012)
  192. Genetic mapping of an autosomal recessive postaxial polydactyly type A to chromosome 13q13.3-q21.2 and screening of the candidate genes. Umm-e-Kalsoom, Basit S, Kamran-ul-Hassan Naqvi S, Ansar M, Ahmad W. Hum. Genet. 131 415-422 (2012)
  193. Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression. Maritz MF, van der Watt PJ, Holderness N, Birrer MJ, Leaner VD. Biol. Chem. 392 439-448 (2011)
  194. UV-Laser induced protein/DNA crosslinking reveals sequence variations of DNA elements bound by c-Jun in vivo. Santoro R, Wölfl S, Saluz HP. Biochem. Biophys. Res. Commun. 256 68-74 (1999)
  195. The AP-1 transcription factor homolog Pf-AP-1 activates transcription of multiple biomineral proteins and potentially participates in Pinctada fucata biomineralization. Zheng X, Cheng M, Xiang L, Liang J, Xie L, Zhang R. Sci Rep 5 14408 (2015)
  196. Cyclodextrin-peptide conjugates for sequence specific DNA binding. Ruiz García Y, Zelenka J, Pabon YV, Iyer A, Buděšínský M, Kraus T, Smith CI, Madder A. Org. Biomol. Chem. 13 5273-5278 (2015)
  197. The Aspergillus nidulans metZ gene encodes a transcription factor involved in regulation of sulfur metabolism in this fungus and other Eurotiales. Piłsyk S, Natorff R, Sieńko M, Skoneczny M, Paszewski A, Brzywczy J. Curr. Genet. 61 115-125 (2015)
  198. Threonine 149 phosphorylation enhances ΔFosB transcriptional activity to control psychomotor responses to cocaine. Cates HM, Thibault M, Pfau M, Heller E, Eagle A, Gajewski P, Bagot R, Colangelo C, Abbott T, Rudenko G, Neve R, Nestler EJ, Robison AJ. J. Neurosci. 34 11461-11469 (2014)
  199. AP-1 Gene Expression Levels May Be Correlated with Changes in Gene Expression of Some Stemness Factors in Colon Carcinomas. Apostolou P, Toloudi M, Ioannou E, Chatziioannou M, Kourtidou E, Vlachou I, Papasotiriou I. J Signal Transduct 2013 497383 (2013)
  200. Opposite orientations of a transcription factor heterodimer bind DNA cooperatively with interaction partners but have different effects on interferon-β gene transcription. Burns V, Kerppola TK. J. Biol. Chem. 287 31833-31844 (2012)
  201. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Tsai YC, Greco TM, Boonmee A, Miteva Y, Cristea IM. Mol. Cell Proteomics 11 M111.015156 (2012)
  202. The effect of JDP2 and ATF2 on the epithelial-mesenchymal transition of human pancreatic cancer cell lines. Xu Y, Liu Z, Guo K. Pathol. Oncol. Res. 18 571-577 (2012)
  203. Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1. Bigalke JM, Dames SA, Blankenfeldt W, Grzesiek S, Geyer M. J. Mol. Biol. 414 639-653 (2011)
  204. Dissecting the role of leucine zippers in the binding of bZIP domains of Jun transcription factor to DNA. Seldeen KL, McDonald CB, Deegan BJ, Bhat V, Farooq A. Biochem. Biophys. Res. Commun. 394 1030-1035 (2010)
  205. An engineered right-handed coiled coil domain imparts extreme thermostability to the KcsA channel. Yuchi Z, Pau VP, Lu BX, Junop M, Yang DS. FEBS J. 276 6236-6246 (2009)
  206. A new method for the construction of a mutant library with a predictable occurrence rate using Poisson distribution. Seong KM, Park H, Kim SJ, Ha HN, Lee JY, Kim J. J. Microbiol. Methods 69 442-450 (2007)
  207. Identification and characterization of the DNA-binding properties of a Zhangfei homologue in Japanese pufferfish, Takifugu rubripes. Cockram GP, Hogan MR, Burnett HF, Lu R. Biochem. Biophys. Res. Commun. 339 1238-1245 (2006)
  208. Addition of positively charged tripeptide to N-terminus of the Fos basic region leucine zipper domain: implications on DNA bending, affinity, and specificity. Mahmoudi T, Sarkar B. Biopolymers 50 273-286 (1999)
  209. Expression, purification and characterization of a novel bZIP protein from sugarcane. Schlogl PS, Kobarg J, Moreau VH, Leite A, Sabino AA, Eberlin MN, Menossi M. Plant Sci. 167 583-595 (2004)
  210. Crystallization and preliminary X-Ray diffraction analysis of the 190-A-long coiled-coil dimerization domain of the actin-bundling protein cortexillin I from dictyostelium discoideum Burkhard P, Steinmetz MO, Schulthess T, Landwehr R, Aebi U, Kammerer RA. J. Struct. Biol. 122 293-296 (1998)
  211. Solution structure of the ATF-2 recognition site and its interaction with the ATF-2 peptide. Conte MR, Lane AN, Bloomberg G. Nucleic Acids Res. 25 3808-3815 (1997)
  212. Simultaneous binding of a polyamide dimer and an oligonucleotide in the minor and major grooves of DNA. Parks ME, Dervan PB. Bioorg. Med. Chem. 4 1045-1050 (1996)
  213. Genome-wide analyses of the bZIP family reveal their involvement in the development, ripening and abiotic stress response in banana. Hu W, Wang L, Tie W, Yan Y, Ding Z, Liu J, Li M, Peng M, Xu B, Jin Z. Sci Rep 6 30203 (2016)
  214. Diphlorethohydroxycarmalol Suppresses Ultraviolet B-Induced Matrix Metalloproteinases via Inhibition of JNK and ERK Signaling in Human Keratinocytes. Piao MJ, Susara Ruwan Kumara MH, Kim KC, Kang KA, Kang HK, Lee NH, Hyun JW. Biomol Ther (Seoul) 23 557-563 (2015)
  215. Evidence for Homodimerization of the c-Fos Transcription Factor in Live Cells Revealed by Fluorescence Microscopy and Computer Modeling. Szalóki N, Krieger JW, Komáromi I, Tóth K, Vámosi G. Mol. Cell. Biol. 35 3785-3798 (2015)
  216. Peptide-DNA conjugates as tailored bivalent binders of the oncoprotein c-Jun. Pazos E, Portela C, Penas C, Vázquez ME, Mascareñas JL. Org. Biomol. Chem. 13 5385-5390 (2015)
  217. The newly characterized Pl-jun is specifically expressed in skeletogenic cells of the Paracentrotus lividus sea urchin embryo. Russo R, Pinsino A, Costa C, Bonaventura R, Matranga V, Zito F. FEBS J. 281 3828-3843 (2014)
  218. Controlling leucine-zipper partner recognition in cells through modification of a-g interactions. Azuma Y, Kükenshöner T, Ma G, Yasunaga J, Imanishi M, Tanaka G, Nakase I, Maruno T, Kobayashi Y, Arndt KM, Matsuoka M, Futaki S. Chem. Commun. (Camb.) 50 6364-6367 (2014)
  219. Flexibility of the linker between the domains of DNA methyltransferase SsoII revealed by small-angle X-ray scattering: implications for transcription regulation in SsoII restriction-modification system. Konarev PV, Kachalova GS, Ryazanova AY, Kubareva EA, Karyagina AS, Bartunik HD, Svergun DI. PLoS ONE 9 e93453 (2014)
  220. Design of a bZip transcription factor with homo/heterodimer-induced DNA-binding preference. Pogenberg V, Consani Textor L, Vanhille L, Holton SJ, Sieweke MH, Wilmanns M. Structure 22 466-477 (2014)
  221. Baicalein Attenuates Oxidative Stress-Induced Expression of Matrix Metalloproteinase-1 by Regulating the ERK/JNK/AP-1 Pathway in Human Keratinocytes. Kim KC, Kang SS, Lee J, Park D, Hyun JW. Biomol Ther (Seoul) 20 57-61 (2012)
  222. Kinetic analysis of cytokine-mediated receptor assembly using engineered FC heterodimers. Deshpande A, Putcha BD, Kuruganti S, Walter MR. Protein Sci. 22 1100-1108 (2013)
  223. Forced homodimerization of the c-Fos leucine zipper in designed bHLHZ-like hybrid proteins MaxbHLH-Fos and ArntbHLH-Fos. Chen G, De Jong AT, Shin JA. Mol Biosyst 8 1286-1296 (2012)
  224. DNA plasticity is a key determinant of the energetics of binding of Jun-Fos heterodimeric transcription factor to genetic variants of TGACGTCA motif. Seldeen KL, McDonald CB, Deegan BJ, Bhat V, Farooq A. Biochemistry 48 12213-12222 (2009)
  225. Hydrophobic scale: a second parameter to elucidating various specific ligand-protein interactions. Numao N, Fujii H, Fukazawa Y, Hanagata N, Tanaka K. Chem. Pharm. Bull. 52 377-379 (2004)
  226. Electrostatic control of half-site spacing preferences by the cyclic AMP response element-binding protein CREB. Montclare JK, Sloan LS, Schepartz A. Nucleic Acids Res. 29 3311-3319 (2001)
  227. Solution structure of O-glycosylated C-terminal leucine zipper domain of human salivary mucin (MUC7). Narasimhamurthy S, Naganagowda GA, Janagani S, Gururaja TL, Levine MJ. J. Biomol. Struct. Dyn. 18 145-154 (2000)
  228. Identification of c-Fos as a mitotic phosphoprotein: regulation of c-Fos by Aurora-A. Yu CT, Wu JC, Liao MC, Hsu SL, Huang CY. J. Biomed. Sci. 15 79-87 (2008)
  229. Letter NMR spectroscopy and X-ray crystallography provide complementary information on the structure and dynamics of leucine zippers. King GF. Biophys. J. 71 1152-1154 (1996)
  230. Mutant bZip-DNA complexes with four quasi-identical protein-DNA interfaces. Suckow M, Lopata M, Seydel A, Kisters-Woike B, von Wilcken-Bergmann B, Müller-Hill B. EMBO J. 15 598-606 (1996)
  231. Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma. Giuliano A, Swift R, Arthurs C, Marote G, Abramo F, McKay J, Thomson C, Beltran M, Millar M, Priestnall S, Dobson J, Costantino-Casas F, Petrou T, McGonnell IM, Davies AJ, Weetman M, Garden OA, Masters JR, Thrasivoulou C, Ahmed A. PLoS ONE 11 e0161103 (2016)
  232. Expression of the Robo4 receptor in endothelial cells is regulated by two AP-1 protein complexes. Okada Y, Naruse H, Tanaka T, Funahashi N, Regan ER, Yamakawa K, Hino N, Ishimoto K, Doi T, Aird WC. Biochem. Biophys. Res. Commun. 467 987-991 (2015)
  233. Imaging Fos-Jun transcription factor mobility and interaction in live cells by single plane illumination-fluorescence cross correlation spectroscopy. Pernuš A, Langowski J. PLoS ONE 10 e0123070 (2015)
  234. Determination of oligomeric states of peptide complexes using thermal unfolding curves. Rabe M, Boyle A, Zope HR, Versluis F, Kros A. Biopolymers 104 65-72 (2015)
  235. Emergence of structure through protein-protein interactions and pH changes in dually predicted coiled-coil and disordered regions of centrosomal proteins. Treviño MA, García-Mayoral MF, Jiménez MÁ, Bastolla U, Bruix M. Biochim. Biophys. Acta 1844 1808-1819 (2014)
  236. Construction, expression, and purification of recombinant αVβ5 integrin. Tartaglia LJ, Bennett A, Woodhouse AG, Aydemir F, Muzyczka N, Agbandje-McKenna M. Protein Expr. Purif. 89 225-231 (2013)
  237. Activating transcription factor 2 targets c-Fos, but not c-Jun, in growth plate chondrocytes. Li X, LuValle P. J. Cell. Biochem. 112 211-216 (2011)
  238. FIAT, the factor-inhibiting ATF4-mediated transcription, also represses the transcriptional activity of the bZIP factor FRA-1. St-Arnaud R, Mandic V, Elchaarani B. Ann. N. Y. Acad. Sci. 1192 338-343 (2010)
  239. Reengineering natural design by rational design and in vivo library selection: the HLH subdomain in bHLHZ proteins is a unique requirement for DNA-binding function. Xu J, De Jong AT, Chen G, Chow HK, Damaso CO, Schwartz Mittelman A, Shin JA. Protein Eng. Des. Sel. 23 337-346 (2010)
  240. Minimalist proteins: Design of new molecular recognition scaffolds. Shin JA. Pure Appl. Chem. 76 1579-1590 (2004)
  241. Recombination system based on cre alpha complementation and leucine zipper fusions. Seidi A, Mie M, Kobatake E. Appl. Biochem. Biotechnol. 158 334-342 (2009)
  242. Solution structure of the orphan nuclear receptor rev-erb beta response element by 1H, 31P NMR and molecular simulation*. Castagné C, Terenzi H, Zakin MM, Delepierre M. Biochimie 82 739-748 (2000)
  243. Dual DNA recognition codes of a short peptide derived from the basic leucine zipper protein EmBP1. Hirata A, Ueno M, Aizawa Y, Ohkubo K, Morii T, Yoshikawa S. Bioorg. Med. Chem. 13 3107-3116 (2005)
  244. Design and characterization of a multimeric DNA binding protein using Sac7d and GCN4 as templates. Wu SW, Ko TP, Chou CC, Wang AH. Proteins 60 617-628 (2005)
  245. Application of complex demodulation on bZIP and bHLH-PAS protein domains. Wang Z, Smith CE, Atchley WR. Math Biosci 207 204-218 (2007)
  246. New developments in the synthesis of oligonucleotide-peptide conjugates. Portela C, Mascareñas JL, Albericio F, Mazzini S, Caminal C, Ramos R, Ocampo SM, Eritja R. Nucleosides Nucleotides Nucleic Acids 26 963-967 (2007)
  247. Energetic coupling along an allosteric communication channel drives the binding of Jun-Fos heterodimeric transcription factor to DNA. Seldeen KL, Deegan BJ, Bhat V, Mikles DC, McDonald CB, Farooq A. FEBS J. 278 2090-2104 (2011)
  248. Veritas per structuram. Harrison SC. Annu. Rev. Biochem. 84 37-60 (2015)
  249. Bag-1 promotes cell survival through c-Myc-mediated ODC upregulation that is not preferred under apoptotic stimuli in MCF-7 cells. Ozfiliz P, Kizilboga T, Demir S, Alkurt G, Palavan-Unsal N, Arisan ED, Dinler-Doganay G. Cell Biochem. Funct. 33 293-307 (2015)
  250. Purinergic P2Y2 Receptor Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: NEW AP-1 TRANSCRIPTION FACTOR SITE AND NEGATIVE REGULATOR. Liu Y, Zhang L, Wang C, Roy S, Shen J. J. Biol. Chem. 291 1553-1563 (2016)
  251. KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation. Han XR, Zha Z, Yuan HX, Feng X, Xia YK, Lei QY, Guan KL, Xiong Y. Oncogene 35 4179-4190 (2016)
  252. The Orientations of Large Aspect-Ratio Coiled-Coil Proteins Attached to Gold Nanostructures. Chang JB, Kim YH, Thompson E, No YH, Kim NH, Arrieta J, Manfrinato VR, Keating AE, Berggren KK. Small 12 1498-1505 (2016)
  253. Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator. Rajasekar KV, Lovering AL, Dancea F, Scott DJ, Harris SA, Bingle LE, Roessle M, Thomas CM, Hyde EI, White SA. Nucleic Acids Res. 44 4947-4956 (2016)
  254. 8-Oxoguanine Affects DNA Backbone Conformation in the EcoRI Recognition Site and Inhibits Its Cleavage by the Enzyme. Hoppins JJ, Gruber DR, Miears HL, Kiryutin AS, Kasymov RD, Petrova DV, Endutkin AV, Popov AV, Yurkovskaya AV, Fedechkin SO, Brockerman JA, Zharkov DO, Smirnov SL. PLoS ONE 11 e0164424 (2016)
  255. The DNA target determines the dimerization partner selected by bHLHZ-like hybrid proteins AhRJun and ArntFos. Inamoto I, Chen G, Shin JA. Mol Biosyst 13 476-488 (2017)
  256. Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X. Nucleic Acids Res. 45 2503-2515 (2017)
  257. Heterochiral Jun and Fos bZIP peptides form a coiled-coil heterodimer that is competent for DNA binding. Kamada R, Nakagawa N, Oyama T, Sakaguchi K. J. Pept. Sci. (2017)
  258. Synthesis and FTIR conformational studies of peptides from the basic region of c-Jun: a critical analysis on the basis of CD and NMR data. Dahmani B, Krebs D, el Antri S, Troalen F, Fermandjian S. J. Biomol. Struct. Dyn. 14 429-439 (1997)
  259. The role of interhelical ionic interactions in myosin rod assembly. Arrizubieta MJ, Bandman E. Biochem. Biophys. Res. Commun. 244 588-593 (1998)