Structure analysis

TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES

X-ray diffraction
3.05Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules
2 distinct DNA molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer

Binding statistics and energies are not available for this assembly
Assembly 2
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Multimeric state: hetero tetramer

Binding statistics and energies are not available for this assembly

Macromolecules

Chains: F, H
Length: 62 amino acids
Theoretical weight: 7.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05412 (Residues: 254-315; Coverage: 19%)
Gene name: JUN
InterPro:
CATH: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
SCOP: Leucine zipper domain

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Chains: E, G
Length: 62 amino acids
Theoretical weight: 7.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01100 (Residues: 139-200; Coverage: 16%)
Gene names: FOS, G0S7
InterPro:
CATH: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
SCOP: Leucine zipper domain

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Name: DNA (5'-D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP*A)-3')
Representative chains: A, C
Length: 20 nucleotides
Theoretical weight: 6.27 KDa

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Name: DNA (5'-D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP*T)-3')
Representative chains: B, D
Length: 20 nucleotides
Theoretical weight: 5.99 KDa

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