PDBe 1fmk

X-ray diffraction
1.5Å resolution

CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC

Released:
Source organism: Homo sapiens
Primary publication:
Three-dimensional structure of the tyrosine kinase c-Src.
Nature 385 595-602 (1997)
PMID: 9024657

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proto-oncogene tyrosine-protein kinase Src Chain: A
Molecule details ›
Chain: A
Length: 452 amino acids
Theoretical weight: 51.71 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P12931 (Residues: 86-536; Coverage: 84%)
Gene names: SRC, SRC1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 51.759Å b: 87.38Å c: 101.295Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.264
Expression system: unidentified baculovirus