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STRUCTURE OF E-CADHERIN DOUBLE DOMAIN

X-ray diffraction
2.93Å resolution
PDB entry 1ff5 coloured by chain, front view.
PDB entry 1ff5 coloured by chain, side view.
PDB entry 1ff5 coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Cadherin-1
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Multimeric state: homo dimer
Accessible surface area: 22522.65 Å2
Buried surface area: 2314.19 Å2
Dissociation area: 1,063.09 Å2
Dissociation energy (ΔGdiss): 2.09 kcal/mol
Dissociation entropy (TΔSdiss): 13.38 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-140757

Macromolecules

Cadherin-1
Chains: A, B
Length: 219 amino acids
Theoretical weight: 23.92 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P09803 (Residues: 157-374; Coverage: 25%)
Gene name: Cdh1
Pfam: Cadherin domain
InterPro:
CATH: Cadherins
SCOP: Cadherin
Cadherin-1 in PDB entry 1ff5, assembly 1, front view.
Cadherin-1 in PDB entry 1ff5, assembly 1, side view.
Cadherin-1 in PDB entry 1ff5, assembly 1, top view.
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