PDBe 1fcy

X-ray diffraction
1.3Å resolution

ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARBETA/GAMMA-SELECTIVE RETINOID CD564

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinoic acid receptor gamma Chain: A
Molecule details ›
Chain: A
Length: 236 amino acids
Theoretical weight: 26.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13631 (Residues: 183-417; Coverage: 52%)
Gene names: NR1B3, RARG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P41212
Unit cell:
a: 59.849Å b: 59.849Å c: 155.158Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.134 0.133 0.164
Expression system: Escherichia coli