PDBe 1fcu

X-ray diffraction
2.1Å resolution

CRYSTAL STRUCTURE (TRIGONAL) OF BEE VENOM HYALURONIDASE

Released:

Function and Biology Details

Reaction catalysed:
Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hyaluronidase Chain: A
Molecule details ›
Chain: A
Length: 350 amino acids
Theoretical weight: 40.9 KDa
Source organism: Apis mellifera
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q08169 (Residues: 33-382; Coverage: 99%)
Sequence domains: Hyaluronidase
Structure domains: Aldolase class I

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX7.2
Spacegroup: P3221
Unit cell:
a: 71.157Å b: 71.157Å c: 152.064Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.2 0.257
Expression system: Trichoplusia ni